Macrophages serve as a first line of defense against infection with the facultative
intracellular pathogen, Cryptococcus neoformans (Cn). However, the ability of these innate …

Cryptococcus spp. are human pathogens that cause 181,000 deaths per year. In this work,
we systematically investigated the virulence attributes of Cryptococcus spp. clinical isolates …

Cryptococcus neoformans is an opportunistic human fungal pathogen that elaborates
several virulence attributes, including a polysaccharide capsule and melanin pigments. A …

The Discovery of Melanin Production in Cryptococcus neoformans and its Impact on Diagnosis
and the Study of Virulence Page 1 Zbl. Bakt. 276, 120-123 (1991) © Gustav Fischer Verlag …

Cryptococcus neoformans is an important opportunistic fungal pathogen that causes life-
threatening infection of the central nervous system. A major virulence factor for C …

The cell-wall constituent, melanin, is a virulence factor for pathogenic fungi, but its structural
and mechanistic role is not clearly understood. As intermediates in melanin formation are …

Cryptococcus neoformans is a free-living fungus that is primarily found in soils contaminated
with avian excreta. Recent studies have shown that C. neoformans can synthesize melanins …

The fungal pathogen Cryptococcus neoformans has three major virulence factors: growth at
37° C, capsule synthesis, and melanin formation. Recently in Cell, Liu et al.(2008) employed …

The fungus Cryptococcus neoformans is the causative agent of cryptococcosis, a disease
that is uniformly lethal unless treated with antifungal drugs, yet current regimens are …

In recent years, lipids have been shown to act as signalling molecules not only in
mammalian cells but also in many other eukaryotes. Whereas in mammalian cells lipids …