[HTML][HTML] Lipid biosynthesis as an antifungal target

J Pan, C Hu, JH Yu - Journal of Fungi, 2018 - mdpi.com
Lipids, commonly including phospholipids, sphingolipids, fatty acids, sterols, and
triacylglycerols (TAGs), are important biomolecules for the viability of all cells …

[HTML][HTML] Functional Analysis of the Melanin-Associated Gene CmMR1 in Coniothyrium minitans

C Luo, H Zhao, X Yang, C Qiang, J Cheng… - Frontiers in …, 2018 - frontiersin.org
Coniothyrium minitans is a sclerotial parasite, which has been investigated for commercial
control of crop diseases caused by Sclerotinia sclerotiorum. Previously, we obtained a T …

Depletion of Extracellular Chemokines by Aspergillus Melanin

KT Graf, H Liu, SG Filler, VM Bruno - mBio, 2023 - Am Soc Microbiol
Aspergillus fumigatus is an environmental fungus that can cause life-threatening pulmonary
disease. Infections initiate when conidia are inhaled and land deep inside the small airways …

Conidial melanin of the human-pathogenic fungus Aspergillus fumigatus disrupts cell autonomous defenses in amoebae

I Ferling, JD Dunn, A Ferling, T Soldati, F Hillmann - MBio, 2020 - Am Soc Microbiol
The human-pathogenic fungus Aspergillus fumigatus is a ubiquitous saprophyte that causes
fatal lung infections in immunocompromised individuals. Following inhalation, conidia are …

Peroxisomal and mitochondrial β-oxidation pathways influence the virulence of the pathogenic fungus Cryptococcus neoformans

M Kretschmer, J Wang, JW Kronstad - Eukaryotic Cell, 2012 - Am Soc Microbiol
An understanding of the connections between metabolism and elaboration of virulence
factors during host colonization by the human-pathogenic fungus Cryptococcus neoformans …

[HTML][HTML] Pathogenicity and Growth Conditions Modulate Fonsecaea Extracellular Vesicles' Ability to Interact With Macrophages

LO Las-Casas, CLF Marina, RJA de Castro… - Frontiers in Cellular …, 2022 - frontiersin.org
Chromoblastomycosis (CBM) is a chronic cutaneous and subcutaneous mycosis caused by
black, dimorphic, and filamentous fungi of the Dematiaceae family, such as species of the …

Laccase affects the rate of Cryptococcus neoformans nonlytic exocytosis from macrophages

SO Frazão, HR Sousa, LG Silva, JS Folha… - MBio, 2020 - Am Soc Microbiol
Nonlytic exocytosis is a process in which previously ingested microbes are expelled from
host phagocytes with the concomitant survival of both cell types. This process has been …

[HTML][HTML] Fungal pigments and their roles associated with human health

L Lin, J Xu - Journal of Fungi, 2020 - mdpi.com
Fungi can produce myriad secondary metabolites, including pigments. Some of these
pigments play a positive role in human welfare while others are detrimental. This paper …

Melanin as a virulence factor in pathogenic fungi.

A Polak - Mycoses, 1990 - europepmc.org
The pigment melanin is found universally in nature and is attributed to a variety of functions.
In some fungi it is thought to play a decisive role in the determination of virulence. This …

Fluconazole treatment enhances extracellular release of red pigments in the fungus Monascus purpureus

SH Koli, RK Suryawanshi, CD Patil… - FEMS Microbiology …, 2017 - academic.oup.com
Traditional methods for the production of food grade pigments from the fungus Monascus
spp. mostly rely on submerged fermentation. However, the cell-bound nature and …