Review and research gap identification in genetics causes of syndromic and nonsyndromic hearing loss in Saudi Arabia

F Almalki - Annals of Human Genetics, 2024 - Wiley Online Library
Congenital hearing loss is one of the most common sensory disabilities worldwide. The
genetic causes of hearing loss account for 50% of hearing loss. Genetic causes of hearing …

A comprehensive introduction to the genetic basis of non-syndromic hearing loss in the Saudi Arabian population

F Imtiaz, K Taibah, K Ramzan, G Bin-Khamis… - BMC medical …, 2011 - Springer
Background Hearing loss is a clinically and genetically heterogeneous disorder. Mutations
in the DFNB1 locus have been reported to be the most common cause of autosomal …

Genetic spectrum of syndromic and non-syndromic hearing loss in Pakistani families

J Doll, B Vona, L Schnapp, F Rüschendorf, I Khan… - Genes, 2020 - mdpi.com
The current molecular genetic diagnostic rates for hereditary hearing loss (HL) vary
considerably according to the population background. Pakistan and other countries with …

Investigation of the genetic causes of non-syndromic hearing loss in the Western region of Saudi Arabia

K Daghistani, A Abdulkarim, A Bamanie, M Safieh… - BMC Genomics, 2014 - Springer
Background For every thousand children born in the world, there is one who is born with a
hereditary form of hearing loss. In Saudi Arabia, the rate of children affected with …

Global genetic insight contributed by consanguineous Pakistani families segregating hearing loss

EM Richard, RLP Santos‐Cortez, R Faridi… - Human …, 2019 - Wiley Online Library
Consanguineous Pakistani pedigrees segregating deafness have contributed decisively to
the discovery of 31 of the 68 genes associated with nonsyndromic autosomal recessive …

Epidemiology, etiology, genetic variants in non-syndromic hearing loss in Iran: A systematic review and meta‐analysis

F Aliazami, S Gilani, D Farhud, M Naraghi… - International Journal of …, 2023 - Elsevier
Objectives Hearing loss is one of the most common heterogeneous complicated disorders
worldwide. We previously analyzed the results of published data on non-syndromic hearing …

Etiology of hearing loss and genetic hearing loss

SY Kim, BY Choi - Hanyang Medical Reviews, 2015 - synapse.koreamed.org
Hearing loss is one of the most common sensory disorders and has numerous
environmental and genetic factors that influence its onset and development. Hearing loss …

Genetic epidemiology of hearing loss in the 22 Arab countries: a systematic review

M Sidenna, T Fadl, H Zayed - Otology & Neurotology, 2020 - journals.lww.com
Background: Hearing loss (HL) is a heterogeneous condition that causes partial or complete
hearing impairment. Hundreds of variants in more than 60 genes have been reported to be …

A comprehensive study to determine heterogeneity of autosomal recessive nonsyndromic hearing loss in Iran

M Babanejad, Z Fattahi… - American journal of …, 2012 - Wiley Online Library
Hearing loss is the most common sensory disorder worldwide and affects 1 of every 500
newborns. In developed countries, at least 50% of cases are genetic, most often resulting in …

Sequence variants in genes causing nonsyndromic hearing loss in a Pakistani cohort

A Khan, S Han, R Wang, M Ansar… - … Genetics & Genomic …, 2019 - Wiley Online Library
Background Hearing loss or hearing impairment is a clinically and genetically
heterogeneous disorder. More than 117 genes were discovered to date in hereditary …