Background Diabetic nephropathy (DN) is a serious threat to human health, but its
pathogenesis is not fully understood. Otsuka Long-Evans Tokushima Fatty (OLETF) rats are …

To evaluate proteins associated with the development of diabetic nephropathy, a major
cause of the end-stage renal disease, we analyzed protein expression in isolated glomeruli …

Diabetic nephropathy (DN), a common diabetic microvascular complication, is characterized
by progressive glomerular sclerosis and tubulointerstitial fibrosis. However, the underlying …

Objective We aimed to characterize the pathogenesis of diabetic nephropathy (DN) in two
commonly used type 2 diabetes mellitus (T2DM) animal models and explore the preliminary …

Diabetic nephropathy (DN) is a microvascular complication associated with diabetes
causing slow deterioration of kidneys leading to end-stage renal disease. Timely …

Comprehensive insight into the gender-based gene expression-related omics data in a
rodent model of diabetic nephropathy (DN) is scarce. In the present study, the gender-based …

Background. Diabetic nephropathy (DN) is the leading cause of ESRD. Emerging evidence
indicated that proteinuria may not be the determinant of renal survival in DN. The aim of the …

A critical challenge faced by clinical nephrologists today is the escalating number of patients
developing end stage renal disease, a major proportion of which is attributed to diabetic …

To describe gene expression changes that characterize the development of diabetic
nephropathy, we performed microarray and phenotype analysis on kidneys from db/db mice …

Diabetic nephropathy is one of the most serious microvascular complications of diabetes
mellitus, with increasing prevalence and mortality. Currently, renal function is assessed …