Clinical management of breast cancer heterogeneity

D Zardavas, A Irrthum, C Swanton… - Nature reviews Clinical …, 2015 - nature.com
Traditionally, intertumour heterogeneity in breast cancer has been documented in terms of
different histological subtypes, treatment sensitivity profiles, and clinical outcomes among …

Tumor heterogeneity in breast cancer

G Turashvili, E Brogi - Frontiers in medicine, 2017 - frontiersin.org
Breast cancer is a heterogeneous disease and differs greatly among different patients
(intertumor heterogeneity) and even within each individual tumor (intratumor heterogeneity) …

Breast cancer heterogeneity

C Fumagalli, M Barberis - Diagnostics, 2021 - mdpi.com
Breast tumor heterogeneity is a major challenge in the clinical management of breast cancer
patients. Both inter-tumor and intra-tumor heterogeneity imply that each breast cancer (BC) …

Breast cancer heterogeneity and response to novel therapeutics

M Baliu-Piqué, A Pandiella, A Ocana - Cancers, 2020 - mdpi.com
Simple Summary Breast cancer is a heterogeneous disease that is driven by genetic,
epigenetic and phenotypic modifications and is also affected by the microenvironment and …

Tumoral heterogeneity of breast cancer

A Roulot, D Héquet, JM Guinebretière… - Annales de biologie …, 2016 - jle.com
The objective of this literature review is to describe the types of tumor heterogeneity in breast
cancer and their clinical implication. Two kinds of tumor heterogeneity are described …

Heterogeneity in breast cancer

K Polyak - The Journal of clinical investigation, 2011 - Am Soc Clin Investig
Breast cancer is a heterogeneous disease. There is a high degree of diversity between and
within tumors as well as among cancer-bearing individuals, and all of these factors together …

Management of breast cancer with targeted agents: importance of heterogenicity

S Di Cosimo, J Baselga - Nature reviews Clinical oncology, 2010 - nature.com
Breast cancer is a heterogeneous disease with different molecular drivers regulating its
growth, survival and response to therapy. Breast cancer is divided in three major subtypes …

Breast cancer—one term, many entities?

NR Bertos, M Park - The Journal of clinical investigation, 2011 - Am Soc Clin Investig
Breast cancer, rather than constituting a monolithic entity, comprises heterogeneous tumors
with different clinical characteristics, disease courses, and responses to specific treatments …

Tumour heterogeneity of breast cancer: from morphology to personalised medicine

MA Aleskandarany, ME Vandenberghe, C Marchiò… - Pathobiology, 2018 - karger.com
Breast cancer (BC) displays striking clinical, morphological, and behavioural diversity within
a single tumour and between tumours. Currently, mounting evidence indicates that the …

Heterogeneity of breast cancer: The importance of interaction between different tumor cell populations

I Januškevičienė, V Petrikaitė - Life sciences, 2019 - Elsevier
Introduction Breast cancer is the most common cancer and the second leading cause of
cancer-related death in women worldwide. Despite the early detection of breast cancer and …