Purpose We evaluated T helper lymphocyte profile, including novel Th17 subsets Th17. 1
(secrete IFN-γ, associate with corticosteroid resistance) and PD1+ Th17 (secrete TGF-β1 …

Objective Takayasu arteritis (TAK) is a large‐vessel vasculitis that induces damage to the
aorta and its branches. Glucocorticoids remain the gold standard of therapy for TAK. The …

Introduction. Th17, γδT, NK, and NKT cells in peripheral blood and serum IL-17 and IL-23 in
Takayasu arteritis (TA) were measured and correlated with disease activity. Methods. Th17 …

Takayasu's arteritis (TAK) is a type of large vessel vasculitis which involves the aorta and its
major branches. Interleukin (IL)-9 or IL-9-producing Th9 cells were found to be involved in …

The involvement of IL-17A in autoimmune and inflammatory diseases has prompted the
development of therapeutic strategies to block the Th17 pathway. Promising results came …

Objective. To investigate T cell subsets and immune cytokine profiles in untreated Takayasu
arteritis (TAK) patients and the underlying immunopathological mechanism. Methods. We …

There is a growing need for disease related biomarkers in Takayasu arteritis (TA). The
assessment of pro-inflammatory cytokines and chemokines in TA may provide a better …

It is now well established that Th17 lymphocytes associate with myriad immune-mediated
inflammatory diseases. Over the past one and a half decades, a subset of Th17 lymphocytes …

OBJECTIVES: Takayasu's arteritis (TAK) involves inflammatory vasculitis of large vessels
and mainly affects the aorta and its major branches. Abnormal immunity may play a vital role …

OBJECTIVE: Atherosclerosis is a chronic inflammatory disease regulated by T lymphocyte
subsets. Th17 cells reportedly play important roles in the development of inflammatory and …