We have investigated constitutive and phytohaemagglutinin (PHA)+ phorbol 12-myristate 13-
acetate (PMA)-induced gene expression of tumour necrosis factor (TNF)-α, interferon (IFN) …

Objective Giant cell (temporal) arteritis (GCA) is a vasculitis that mainly affects the large and
medium arteries, especially the branches of the proximal aorta. Interleukin‐32 (IL‐32) is a …

Atherosclerosis is a chronic inflammatory disease mediated by innate and adaptive immune
responses. In recent years, CD4+ T cells (Th1, Th2, Treg, and Th17) have been increasingly …

Atherosclerosis is nowadays recognized as a chronic inflammatory disease of large arteries.
In recent years, cellular and molecular biology studies on atherosclerosis confirmed that the …

Newly identified T helper cell 22 (Th22) is a subset of CD4+ T cells with specific properties
apart from other known CD4+ T cell subsets. Th22 is obviously discrete from Th17 and Th1 …

Abstract Type 17 T helper (TH17) cells are a population of CD4+ effector T cells that are
distinct from TH1 and TH2 cells owing to their ability to produce interleukin (IL)-17. Although …

Objective. Rheumatoid arthritis (RA) is a common autoimmune disease that is primarily
driven by effector T cells, particularly Th17 cells, which are mainly contained within CD4+ …

Objective Regulatory T cells (Tregs) with the plasticity of producing proinflammatory cytokine
IL-17 have been demonstrated under normal and pathogenic conditions. However, it …

Objective To investigate the relative abundance and activities of Th17 cells and natural Treg
cells in systemic lupus erythematosus (SLE). Methods Blood samples were collected from …

Background. Evidence from experimental studies showed that Th1, Th2, and Th17 play a
pivotal role in hypertension and target organ damage. However, whether changes in the …