Background Hemodynamic instability and myocardial dysfunction are major factors
preventing the transplantation of hearts from organ donors after brain death. Intravenous …

Hypothesis Levothyroxine sodium therapy should be used in brain-dead potential organ
donors to reverse hemodynamic instability and to prevent cardiovascular collapse, leading …

Background. Brain death results in adverse pathophysiologic effects in many cadaveric
donors, resulting in cardiovascular instability and poor organ perfusion. Hormonal …

Background. Brain death results in cardiovascular instability and poor organ perfusion in
many brain-dead donors. Hormonal resuscitation stabilizes certain brain-dead donors and is …

The aggressive management of brain‐dead (cadaveric) organ donors has been shown to
increase organs available for transplantation. Some centers use hormone therapy with …

Objectives: To review all published clinical studies of thyroid hormone administration to
brain-dead potential organ donors. Methods: A search of PubMed using multiple search …

Background Hormonal therapy to the brain-dead potential organ donor can include thyroid
hormone (triiodothyronine [T 3] or levothyroxine [T 4]), corticosteroids, antidiuretic hormone …

Triiodothyronine deficiency after brain death can result in progressive deterioration of
cardiac function in potential organ donors. We report on the use of triiodothyronine …

Objective We compared hemodynamic values, oxygen utilization, and adenine nucleotide
concentration in the extracted organs of brain-dead donors treated with triiodothyronine vs …

Brain death is associated with neuroendocrine changes, in particular with a significant
reduction of plasma-free triiodothyronine (T3) that results in impaired aerobic metabolism …