[HTML][HTML] Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes
CP Yang, X Li, Y Wu, Q Shen, Y Zeng, Q Xiong… - Nature …, 2018 - nature.com
Recent genome-wide association studies (GWAS) have identified multiple risk loci that show
strong associations with schizophrenia. However, pinpointing the potential causal genes at …
strong associations with schizophrenia. However, pinpointing the potential causal genes at …
[HTML][HTML] The integrated landscape of causal genes and pathways in schizophrenia
C Ma, C Gu, Y Huo, X Li, XJ Luo - Translational psychiatry, 2018 - nature.com
Genome-wide association studies (GWAS) have identified more than 100 loci that show
robust association with schizophrenia risk. However, due to the complexity of linkage …
robust association with schizophrenia risk. However, due to the complexity of linkage …
[HTML][HTML] Functional genomics reveal gene regulatory mechanisms underlying schizophrenia risk
Y Huo, S Li, J Liu, X Li, XJ Luo - Nature communications, 2019 - nature.com
Genome-wide association studies (GWASs) have identified over 180 independent
schizophrenia risk loci. Nevertheless, how the risk variants in the reported loci confer …
schizophrenia risk loci. Nevertheless, how the risk variants in the reported loci confer …
Functional genomics identify a regulatory risk variation rs4420550 in the 16p11. 2 schizophrenia-associated locus
H Chang, X Cai, HJ Li, WP Liu, LJ Zhao, CY Zhang… - Biological …, 2021 - Elsevier
Background Genome-wide association studies (GWASs) have reported hundreds of
genomic loci associated with schizophrenia, yet identifying the functional risk variations is a …
genomic loci associated with schizophrenia, yet identifying the functional risk variations is a …
[HTML][HTML] Genome-wide association study followed by trans-ancestry meta-analysis identify 17 new risk loci for schizophrenia
J Liu, S Li, X Li, W Li, Y Yang, S Guo, L Lv, X Xiao… - BMC medicine, 2021 - Springer
Background Over 200 schizophrenia risk loci have been identified by genome-wide
association studies (GWASs). However, the majority of risk loci were identified in …
association studies (GWASs). However, the majority of risk loci were identified in …
Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis
Genome-wide association studies have identified 108 schizophrenia risk loci, but biological
mechanisms for individual loci are largely unknown. Using developmental, genetic and …
mechanisms for individual loci are largely unknown. Using developmental, genetic and …
[HTML][HTML] Network-assisted investigation of combined causal signals from genome-wide association studies in schizophrenia
With the recent success of genome-wide association studies (GWAS), a wealth of
association data has been accomplished for more than 200 complex diseases/traits …
association data has been accomplished for more than 200 complex diseases/traits …
Genome‐Wide Findings in Schizophrenia and the Role of Gene–Environment Interplay
R Van Winkel, G Esquivel, G Kenis… - CNS neuroscience & …, 2010 - Wiley Online Library
The recent advent of genome‐wide mass‐marker technology has resulted in renewed
optimism to unravel the genetic architecture of psychotic disorders. Genome‐wide …
optimism to unravel the genetic architecture of psychotic disorders. Genome‐wide …
Common variants conferring risk of schizophrenia: a pathway analysis of GWAS data
Unlike the typical analysis of single markers in genome-wide association studies (GWAS),
we incorporated Gene Set Enrichment Analysis (GSEA) and hypergeometric test and …
we incorporated Gene Set Enrichment Analysis (GSEA) and hypergeometric test and …
[HTML][HTML] Comprehensive functional annotation of susceptibility SNPs prioritized 10 genes for schizophrenia
HM Niu, P Yang, HH Chen, RH Hao, SS Dong… - Translational …, 2019 - nature.com
Nearly 95% of susceptibility SNPs identified by genome-wide association studies (GWASs)
are located in non-coding regions, which causes a lot of difficulty in deciphering their …
are located in non-coding regions, which causes a lot of difficulty in deciphering their …