Age-related decline in female fertility is a common feature that occurs in the fourth decade of
women as a result of a reduction in both oocyte quality and quantity [1]. However, strategies …

The quality of postovulatory metaphase II oocytes undergoes a time-dependent deterioration
as a result of the aging process. Melatonin is considered to be an anti-aging agent …

It has been widely reported that advanced maternal age impairs oocyte quality. To date,
various molecules have been discovered to be involved in this process. However …

In mammalian ovaries, oocytes are physically coupled to somatic granulosa cells, and this
coupling is crucial for the growth and development of competent oocytes as it mediates the …

Chronic stress which is common in the current society can be harmful to female reproduction
and is associated with oocyte defects. However, the underlying mechanisms remain largely …

The quality of metaphase II oocytes will undergo a time-dependent deterioration following
ovulation as the result of the oocyte aging process. In this study, we determined that the …

Postovulatory oocyte aging has a major influence on the development potential of embryos.
Many antioxidants can delay oocyte aging by regulating the expression of SIRT1. However …

Ovarian aging is characterized by gradual declines in oocyte quantity and quality. Melatonin
is considered an anti‐aging agent due to its cytoprotective actions as an antioxidant. This …

The quality of metaphase II oocytes deteriorates rapidly following ovulation as the result of
an aging process associated with impaired fertilizing potential, disrupted developmental …

Maternal obesity in humans is associated with poor outcomes across the reproductive
spectrum. Emerging evidence indicates that these defects are likely attributed to factors …