Transcriptional Profiling of Pseudomonas aeruginosa Infections
JG Thöming, S Häussler - Pseudomonas aeruginosa: Biology …, 2022 - Springer
Pseudomonas aeruginosa is an opportunistic pathogen that causes life-devastating acute
as well as chronic biofilm-associated infections with limited treatment options. Its success is …
as well as chronic biofilm-associated infections with limited treatment options. Its success is …
In-Vivo Expression Profiling of Pseudomonas aeruginosa Infections Reveals Niche-Specific and Strain-Independent Transcriptional Programs
P Bielecki, J Puchałka, ML Wos-Oxley, H Loessner… - PloS one, 2011 - journals.plos.org
Pseudomonas aeruginosa is a threatening, opportunistic pathogen causing disease in
immunocompromised individuals. The hallmark of P. aeruginosa virulence is its multi …
immunocompromised individuals. The hallmark of P. aeruginosa virulence is its multi …
A dynamic and intricate regulatory network determines Pseudomonas aeruginosa virulence
D Balasubramanian, L Schneper, H Kumari… - Nucleic acids …, 2013 - academic.oup.com
Pseudomonas aeruginosa is a metabolically versatile bacterium that is found in a wide
range of biotic and abiotic habitats. It is a major human opportunistic pathogen causing …
range of biotic and abiotic habitats. It is a major human opportunistic pathogen causing …
Convergent Within-Host Adaptation of Pseudomonas aeruginosa through the Transcriptional Regulatory Network
YE Gatt, D Savion, T Bamberger, H Margalit - Msystems, 2023 - Am Soc Microbiol
Bacteria adapt to their host by mutating specific genes and by reprogramming their gene
expression. Different strains of a bacterial species often mutate the same genes during …
expression. Different strains of a bacterial species often mutate the same genes during …
The Single-Nucleotide Resolution Transcriptome of Pseudomonas aeruginosa Grown in Body Temperature
One of the hallmarks of opportunistic pathogens is their ability to adjust and respond to a
wide range of environmental and host-associated conditions. The human pathogen …
wide range of environmental and host-associated conditions. The human pathogen …
Bacterial adaptation during chronic infection revealed by independent component analysis of transcriptomic data
Background Bacteria employ a variety of adaptation strategies during the course of chronic
infections. Understanding bacterial adaptation can facilitate the identification of novel drug …
infections. Understanding bacterial adaptation can facilitate the identification of novel drug …
The Pseudomonas aeruginosa transcriptional landscape is shaped by environmental heterogeneity and genetic variation
A Dötsch, M Schniederjans, A Khaledi, K Hornischer… - MBio, 2015 - Am Soc Microbiol
Phenotypic variability among bacteria depends on gene expression in response to different
environments, and it also reflects differences in genomic structure. In this study, we analyzed …
environments, and it also reflects differences in genomic structure. In this study, we analyzed …
Compendium-wide analysis of P. aeruginosa core and accessory genes reveal more nuanced transcriptional patterns
Strains of Pseudomonas aeruginosa, an opportunistic pathogen that causes difficult to treat
infections, have significant genomic heterogeneity including the presence of diverse …
infections, have significant genomic heterogeneity including the presence of diverse …
Ex vivo transcriptional profiling reveals a common set of genes important for the adaptation of Pseudomonas aeruginosa to chronically infected host sites
P Bielecki, U Komor, A Bielecka… - Environmental …, 2013 - Wiley Online Library
The opportunistic bacterium P seudomonas aeruginosa is a major nosocomial pathogen
causing both devastating acute and chronic persistent infections. During the course of an …
causing both devastating acute and chronic persistent infections. During the course of an …
An atlas of the binding specificities of transcription factors in Pseudomonas aeruginosa directs prediction of novel regulators in virulence
A high-throughput systematic evolution of ligands by exponential enrichment assay was
applied to 371 putative TFs in Pseudomonas aeruginosa, which resulted in the robust …
applied to 371 putative TFs in Pseudomonas aeruginosa, which resulted in the robust …