Simple Summary Oocyte in vitro maturation has massive potential for the generation of great
numbers of embryos for research and for the application of assisted reproductive …

Cyclic adenosine monophosphate (cAMP) is an important molecule in signal transduction
within the cell, functioning as a second cell messenger of gonadotrophin stimulation. The …

Cyclic adenosine monophosphate (cAMP) modulators have been used to avoid
spontaneous oocyte maturation and concomitantly improve oocyte developmental …

We investigated effects of invasive adenylate cyclase (iAC), 3-isobutyl-1-methylxanthine
(IBMX) and dibutyryl cyclic AMP (dbcAMP) on porcine oocyte in vitro maturation (IVM), in …

Objective: The purpose of this research was to compare the kinetics and meiotic
advancement of cattle and buffalo oocytes, as well as to see how cAMP modulators affected …

High cAMP levels during in vitro maturation (IVM) have been related to improved blastocyst
yields. Here, we employed the cAMP/cGMP modulators, forskolin, IBMX, and cilostamide …

The present study aims to investigate if prematuration culture (PMC) of ovine oocytes in the
presence of a phosphodiesterase type 3 (PDE3) inhibitor cilostamide can improve the …

Physical removal of mammalian cumulus-oocyte complexes (COCs) from ovarian follicles
results in spontaneous resumption of meiosis, largely because of a decrease in cAMP …

In vitro maturation (IVM) of cumulus-oocyte complexes (COC) results in oocytes with
reduced quality and is still not as efficient as in vivo maturation in most species. One …

Oocyte in vitro maturation (IVM) is an important assisted reproductive technology and
research tool. The adoption of IVM into routine clinical practice has been hindered by its …