Adiposity in middle and old age and risk of death from dementia: 40-year follow-up of 19,000 men in the Whitehall study
AN Allen, R Clarke, M Shipley, DA Leon - Age and Ageing, 2019 - academic.oup.com
Aims and objectives to examine the hypothesis that obesity is protective for dementia, we
compared the associations of death from dementia with body weight and body mass index …
compared the associations of death from dementia with body weight and body mass index …
[HTML][HTML] Body adiposity in later life and the incidence of dementia: the health in men study
Objective To determine if adiposity in later life increases dementia hazard. Methods Cohort
study of 12,047 men aged 65–84 years living in Perth, Australia. Adiposity exposures were …
study of 12,047 men aged 65–84 years living in Perth, Australia. Adiposity exposures were …
[HTML][HTML] Obesity trajectories and risk of dementia: 28 years of follow-up in the Whitehall II Study
A Singh-Manoux, A Dugravot, M Shipley… - Alzheimer's & …, 2018 - Elsevier
Introduction We examined whether obesity at ages 50, 60, and 70 years is associated with
subsequent dementia. Changes in body mass index (BMI) for more than 28 years before …
subsequent dementia. Changes in body mass index (BMI) for more than 28 years before …
Overweight and Obesity in Old Age Are Not Associated with Greater Dementia Risk: (See editorial comments by Dr. David S. Knodman, pp 2349–2350)
AK Dahl, M Löppönen, R Isoaho… - Journal of the …, 2008 - Wiley Online Library
OBJECTIVES: To describe the association between body mass index (BMI) and dementia
risk in older persons. DESIGN: Prospective population‐based study, with 8 years of follow …
risk in older persons. DESIGN: Prospective population‐based study, with 8 years of follow …
Five-decade trajectories in body mass index in relation to dementia death: follow-up of 33,083 male Harvard University alumni
Background: In prospective cohort studies, obesity has been linked with a lower risk of
subsequent dementia. Reverse causality, whereby neurodegeneration preceding overt …
subsequent dementia. Reverse causality, whereby neurodegeneration preceding overt …
37 years of body mass index and dementia: Observations from the prospective population study of women in Gothenburg, Sweden
DR Gustafson, K Bäckman, E Joas… - Journal of …, 2012 - content.iospress.com
Level of adiposity is linked to dementia in epidemiological studies. Overweight and obesity
in mid-and late-life may increase risk for dementia, whereas decline in body weight or body …
in mid-and late-life may increase risk for dementia, whereas decline in body weight or body …
Body mass index and risk of dementia
Given the rapidly growing burden of Alzheimer's disease and other dementias and the
absence of sufficient treatment options [1], strategies to prevent or delay the disease onset …
absence of sufficient treatment options [1], strategies to prevent or delay the disease onset …
Weight change in midlife and risk of mortality from dementia up to 35 years later
BH Strand, AK Wills, EM Langballe… - … Series A: Biomedical …, 2017 - academic.oup.com
Background: The relationship between body mass index (BMI) and dementia is complex and
controversial. This study investigates the association of weight change during midlife and …
controversial. This study investigates the association of weight change during midlife and …
[HTML][HTML] Is metabolic-healthy obesity associated with risk of dementia? An age-stratified analysis of the Whitehall II cohort study
MD Machado-Fragua, S Sabia, A Fayosse, CB Hassen… - BMC medicine, 2023 - Springer
Background Metabolically healthy obesity is hypothesized to be a benign condition but
whether this is the case for dementia remains debated. We examined the role of age at …
whether this is the case for dementia remains debated. We examined the role of age at …
[HTML][HTML] Body mass index in midlife and dementia: systematic review and meta-regression analysis of 589,649 men and women followed in longitudinal studies
Introduction We conducted a meta-analysis of the conflicting epidemiologic evidence on the
association between midlife body mass index (BMI) and dementia. Methods We searched …
association between midlife body mass index (BMI) and dementia. Methods We searched …