Adiposity in middle and old age and risk of death from dementia: 40-year follow-up of 19,000 men in the Whitehall study

AN Allen, R Clarke, M Shipley, DA Leon - Age and Ageing, 2019 - academic.oup.com
Aims and objectives to examine the hypothesis that obesity is protective for dementia, we
compared the associations of death from dementia with body weight and body mass index …

[HTML][HTML] Body adiposity in later life and the incidence of dementia: the health in men study

BD Power, H Alfonso, L Flicker, GJ Hankey, BB Yeap… - PloS one, 2011 - journals.plos.org
Objective To determine if adiposity in later life increases dementia hazard. Methods Cohort
study of 12,047 men aged 65–84 years living in Perth, Australia. Adiposity exposures were …

[HTML][HTML] Obesity trajectories and risk of dementia: 28 years of follow-up in the Whitehall II Study

A Singh-Manoux, A Dugravot, M Shipley… - Alzheimer's & …, 2018 - Elsevier
Introduction We examined whether obesity at ages 50, 60, and 70 years is associated with
subsequent dementia. Changes in body mass index (BMI) for more than 28 years before …

Overweight and Obesity in Old Age Are Not Associated with Greater Dementia Risk: (See editorial comments by Dr. David S. Knodman, pp 2349–2350)

AK Dahl, M Löppönen, R Isoaho… - Journal of the …, 2008 - Wiley Online Library
OBJECTIVES: To describe the association between body mass index (BMI) and dementia
risk in older persons. DESIGN: Prospective population‐based study, with 8 years of follow …

Five-decade trajectories in body mass index in relation to dementia death: follow-up of 33,083 male Harvard University alumni

TC Russ, IM Lee, HD Sesso, G Muniz-Terrera… - International Journal of …, 2019 - nature.com
Background: In prospective cohort studies, obesity has been linked with a lower risk of
subsequent dementia. Reverse causality, whereby neurodegeneration preceding overt …

37 years of body mass index and dementia: Observations from the prospective population study of women in Gothenburg, Sweden

DR Gustafson, K Bäckman, E Joas… - Journal of …, 2012 - content.iospress.com
Level of adiposity is linked to dementia in epidemiological studies. Overweight and obesity
in mid-and late-life may increase risk for dementia, whereas decline in body weight or body …

Body mass index and risk of dementia

M Koch, MK Jensen - Current Opinion in Lipidology, 2018 - journals.lww.com
Given the rapidly growing burden of Alzheimer's disease and other dementias and the
absence of sufficient treatment options [1], strategies to prevent or delay the disease onset …

Weight change in midlife and risk of mortality from dementia up to 35 years later

BH Strand, AK Wills, EM Langballe… - … Series A: Biomedical …, 2017 - academic.oup.com
Background: The relationship between body mass index (BMI) and dementia is complex and
controversial. This study investigates the association of weight change during midlife and …

[HTML][HTML] Is metabolic-healthy obesity associated with risk of dementia? An age-stratified analysis of the Whitehall II cohort study

MD Machado-Fragua, S Sabia, A Fayosse, CB Hassen… - BMC medicine, 2023 - Springer
Background Metabolically healthy obesity is hypothesized to be a benign condition but
whether this is the case for dementia remains debated. We examined the role of age at …

[HTML][HTML] Body mass index in midlife and dementia: systematic review and meta-regression analysis of 589,649 men and women followed in longitudinal studies

E Albanese, LJ Launer, M Egger, MJ Prince… - Alzheimer's & Dementia …, 2017 - Elsevier
Introduction We conducted a meta-analysis of the conflicting epidemiologic evidence on the
association between midlife body mass index (BMI) and dementia. Methods We searched …