The epidemiology of adiposity and dementia

RA Whitmer - Current Alzheimer Research, 2007 - ingentaconnect.com
Adipose tissue is the largest endocrine gland in the body, yet only recently has its role in
neurodegenerative disease been considered. Prospective population level evidence has …

Adiposity indicators and dementia over 32 years in Sweden

DR Gustafson, K Backman, M Waern, S Ostling, X Guo… - Neurology, 2009 - AAN Enterprises
Background: High midlife and late-life adiposity may increase risk for dementia. Late-life
decrease in body mass index (BMI) or body weight within several years of a dementia …

Invited commentary: body mass index and risk of dementia—potential explanations for life-course differences in risk estimates and future research directions

WD Brenowitz - American Journal of Epidemiology, 2021 - academic.oup.com
The relationship between body mass index (BMI) and health outcomes of older adults,
including dementia, remains controversial. Many studies find inverse associations between …

Body mass index, weight change in midlife, and dementia incidence: the Japan Public Health Center‐based Prospective Study

M Tashiro, N Yasuda, M Inoue… - Alzheimer's & …, 2023 - Wiley Online Library
INTRODUCTION Insufficient evidence exists on the sex‐specific associations of body mass
index (BMI) and weight change through midlife with dementia incidence, especially in Asian …

Measures of adiposity and dementia risk in elderly persons

JA Luchsinger, B Patel, MX Tang, N Schupf… - Archives of …, 2007 - jamanetwork.com
Background Studies relating adiposity to dementia are conflicting. We explored the
associations of body mass index (BMI),(calculated as weight in kilograms divided by the …

Obesity in late-life as a protective factor against dementia and dementia-related mortality

G Natale, Y Zhang, DW Hanes… - American Journal of …, 2023 - journals.sagepub.com
Objective We estimated the conversion from cognitively normal to mild cognitive impairment
(MCI) to probable dementia and death for underweight, normal, overweight, and obese older …

Central obesity in the elderly is related to late-onset Alzheimer disease

JA Luchsinger, D Cheng, MX Tang… - Alzheimer Disease & …, 2012 - journals.lww.com
The evidence relating obesity measured with body mass index (BMI) in the elderly to late-
onset Alzheimer disease (LOAD) is conflicting. Central obesity in middle age is related to a …

Adiposity and the risk of dementia: mediating effects from inflammation and lipid levels

IK Karlsson, Y Zhan, Y Wang, X Li, J Jylhävä… - European Journal of …, 2022 - Springer
While midlife adiposity is a risk factor for dementia, adiposity in late-life appears to be
associated with lower risk. What drives the associations is poorly understood, especially the …

Sex-differential associations between body mass index and the incidence of dementia

L Jacob, L Smith, A Koyanagi, M Konrad… - Journal of …, 2022 - content.iospress.com
Background: Little is known about the sex differences in the association between body mass
index (BMI) and dementia in late life. Objective: Therefore, this retrospective cohort study …

Body adiposity in late life and risk of dementia or cognitive impairment in a longitudinal community-based study

NA West, MN Haan - Journals of Gerontology Series A …, 2009 - academic.oup.com
Background The association between body adiposity at older ages and the development of
cognitive impairment is unclear. Methods The association of body mass index (BMI) and …