Chitosan is a natural, biodegradable cationic polysaccharide, which has a similar chemical
structure and similar biological behaviors to the components of the extracellular matrix in the …

Natural bone tissue is composed of calcium-deficient carbonated hydroxyapatite as the
inorganic phase and collagen type I as the main organic phase. The biomimetic approach of …

Chitosan is a deacetylated polysaccharide from chitin, the natural biopolymer primarily
found in shells of marine crustaceans and fungi cell walls. Upon deacetylation, the …

Chitin and chitosan based nanocomposite scaffolds have been widely used for bone tissue
engineering. These chitin and chitosan based scaffolds were reinforced with …

Bone defect is usually difficult to recover quickly, and bone scaffold transplantation is
considered to be an effective method. Biomaterials have a wide range of application …

The bone is a highly dynamic tissue with the remarkable ability to remodel and is in a
continuous cycle of resorption and renewal as a result of internal mediators and external …

Chitosan-based nanocomplexes with various forms were prepared by ionically crosslinking
with tripolyphosphate (TPP) in different acidic media under mild conditions. It was found that …

In recent years, there has been a substantial rise in the use of nanomaterials in tissue
engineering applications. Nanostructured scaffolds with cells provide a more structurally …

Bone defects requiring grafts to promote healing are frequently occurring and costly
problems in health care. Chitosan, a biodegradable, naturally occurring polymer, has drawn …

Critical-sized bone defects treated with biomaterials offer an efficient alternative to traditional
methods involving surgical reconstruction, allografts, and metal implants. Chitosan, a natural …