[HTML][HTML] Differential antifungal activity of human and cryptococcal melanins with structural discrepancies

N Correa, C Covarrubias, PI Rodas… - Frontiers in …, 2017 - frontiersin.org
Melanin is a pigment found in all biological kingdoms, and plays a key role in protection
against ultraviolet radiation, oxidizing agents, and ionizing radiation damage. Melanin exerts …

Melanin and its role on the virulence of Cryptococcus neoformans

S Alp - Mikrobiyoloji bulteni, 2010 - europepmc.org
Melanins can be produced by some species of pathogenic bacteria, helminths and fungi.
The production of melanin appears to contribute to microbial pathogenesis owing to its …

Melanin as a potential cryptococcal defence against microbicidal proteins

TL Doering, JD Nosanchuk, WK Roberts… - Medical …, 1999 - Taylor & Francis
Cryptococcus neoformans is an important fungal pathogen that synthesizes melanin when
grown in the presence of phenolic substrates. The ability of C. neoformans to produce …

Microstructure of Cell Wall-Associated Melanin in the Human Pathogenic Fungus Cryptococcus neoformans

HC Eisenman, JD Nosanchuk, JBW Webber… - Biochemistry, 2005 - ACS Publications
Melanin is a virulence factor for many pathogenic fungal species, including Cryptococcus
neoformans. Melanin is deposited in the cell wall, and melanin isolated from this fungus …

Impact of melanin on microbial virulence and clinical resistance to antimicrobial compounds

JD Nosanchuk, A Casadevall - Antimicrobial agents and …, 2006 - Am Soc Microbiol
Melanins are negatively charged, hydrophobic pigments of high molecular weight (54, 88,
95, 139) that are composed of polymerized phenolic and/or indolic compounds (Fig. 1)(45 …

[HTML][HTML] Fungal melanin and the mammalian immune system

S Liu, S Youngchim, D Zamith-Miranda, JD Nosanchuk - Journal of Fungi, 2021 - mdpi.com
Melanins are ubiquitous complex polymers that are commonly known in humans to cause
pigmentation of our skin. Melanins are also present in bacteria, fungi, and helminths. In this …

[HTML][HTML] The structural unit of melanin in the cell wall of the fungal pathogen Cryptococcus neoformans

E Camacho, R Vij, C Chrissian… - Journal of Biological …, 2019 - ASBMB
Melanins are synthesized macromolecules that are found in all biological kingdoms. These
pigments have a myriad of roles that range from microbial virulence to key components of …

An alternative method for the analysis of melanin production in Cryptococcus neoformans sensu lato and Cryptococcus gattii sensu lato

RSN Brilhante, JDA España, LP de Alencar… - Mycoses, 2017 - Wiley Online Library
Melanin is an important virulence factor for several microorganisms, including Cryptococcus
neoformans sensu lato and Cryptococcus gattii sensu lato, thus, the assessment of melanin …

[PDF][PDF] Isolation, characterisation and biological activity of melanin from Exidia nigricans

Ł Łopusiewicz - World Scientific News, 2018 - bibliotekanauki.pl
The aim of present study was isolation and characteriation of raw and purified melanin from
Exidia nigricans. Native melanin was isolated from the fresh E. nigricans fruiting bodies by …

Melanin and fungi

BL Gómez, JD Nosanchuk - Current opinion in infectious diseases, 2003 - journals.lww.com
Melanin has been referred to as 'fungal armor'due to the ability of the polymer to protect
microorganisms against a broad range of toxic insults. Recent publications continue to …