Brown and beige adipose tissue: a novel therapeutic strategy for obesity and type 2 diabetes mellitus

L Cheng, J Wang, H Dai, Y Duan, Y An, L Shi, Y Lv… - Adipocyte, 2021 - Taylor & Francis
Mammalian adipose tissue can be divided into two major types, namely, white adipose
tissue (WAT) and brown adipose tissue (BAT). According to classical view, the main function …

The beige adipocyte as a therapy for metabolic diseases

F Lizcano - International journal of molecular sciences, 2019 - mdpi.com
Adipose tissue is traditionally categorized into white and brown relating to their function and
morphology. The classical white adipose tissue builds up energy in the form of triglycerides …

Beiging of white adipose tissue as a therapeutic strategy for weight loss in humans

B Thyagarajan, MT Foster - Hormone molecular biology and clinical …, 2017 - degruyter.com
An imbalance between energy intake and expenditure leads to obesity. Adiposity associated
with obesity progressively causes inflammation, type 2 diabetes, hypertension …

Adipose tissue browning and metabolic health

A Bartelt, J Heeren - Nature Reviews Endocrinology, 2014 - nature.com
Accumulation of excess white adipose tissue (WAT) has deleterious consequences for
metabolic health. The activation of brown adipose tissue (BAT), the primary organ for heat …

[HTML][HTML] Distinction of white, beige and brown adipocytes derived from mesenchymal stem cells

A Park, WK Kim, KH Bae - World journal of stem cells, 2014 - ncbi.nlm.nih.gov
Adipose tissue is a major metabolic organ, and it has been traditionally classified as either
white adipose tissue (WAT) or brown adipose tissue (BAT). WAT and BAT are characterized …

[HTML][HTML] Browning of white fat: agents and implications for beige adipose tissue to type 2 diabetes

A Kaisanlahti, T Glumoff - Journal of physiology and biochemistry, 2019 - Springer
Mammalian adipose tissue is traditionally categorized into white and brown relating to their
function and morphology: while white serves as an energy storage, brown adipose tissue …

From white to beige adipocytes: therapeutic potential of dietary molecules against obesity and their molecular mechanisms

S Wang, MH Pan, WL Hung, YC Tung, CT Ho - Food & function, 2019 - pubs.rsc.org
The global incidence of obesity and its complications continue to rise along with a demand
for novel therapeutic approaches. In addition to classic brown adipose tissue (BAT), the …

Beige fat maintenance; toward a sustained metabolic health

A Rabiee - Frontiers in endocrinology, 2020 - frontiersin.org
Understanding the mammalian energy balance can pave the way for future therapeutics that
enhance energy expenditure as an anti-obesity and anti-diabetic strategy. Several studies …

Brown fat and browning for the treatment of obesity and related metabolic disorders

SH Kim, J Plutzky - Diabetes & metabolism journal, 2016 - synapse.koreamed.org
Brown fat is a specialized fat depot that can increase energy expenditure and produce heat.
After the recent discovery of the presence of active brown fat in human adults and novel …

Browning of white fat: novel insight into factors, mechanisms, and therapeutics

N Jeremic, P Chaturvedi… - Journal of cellular …, 2017 - Wiley Online Library
What is more interesting about brown adipose tissue (BAT) is its ability to provide
thermogenesis, protection against obesity by clearing triglycerides, releasing batokines, and …