The overall aim of this thesis was to increase understanding of physiological responses to
altitude and identify modifiable factors that could enhance health and exercise performance …

Introduction Nitrate supplementation in the form of beetroot juice (BRJ) ingestion has been
shown to improve exercise tolerance during acute hypoxia, but its effect on exercise …

Dietary nitrate supplementation enhances sea level performance and may ameliorate
hypoxemia at high altitude. However, nitrate may exacerbate acute mountain sickness …

Ascent to altitude uniformly reduces exercise capacity. Even following acclimatization,
maximal oxygen consumption (VO2max) remains well below sea level values (Calbet et al …

There is wide inter-individual variability in the reduction of exercise capacity at altitude, and
the factors underlying this remain obscure. In this thesis, I used well-validated …

Cognitive dysfunction at high altitude (HA) may result from suboptimal matching of oxygen
supply to neural demand (ie neurovascular coupling [NVC]). NVC is modulated by nitric …

Studies performed over the past decade have yielded new information related to the
physiological and metabolic adjustments made in response to both shortand long-term high …

Background: Exercise performance data of numerous altitude research studies and
competitive sporting events of the last four decades are reviewed. Methods: The primary …

GARDNER, BD Does altitude training benefit the sea-level performance of athletes?
Purpose: The review was conducted to provide an insight into the possible benefits altitude …

Despite equivocal findings about the benefit of altitude training, current theory dictates that
the best approach is to spend several weeks living at≥ 2500 m but training near sea level …