Editorial Above 90% of lead molecules first tested in phase I studies often fails to reach the
market. Many thousands of compounds do not even complete clinical trials, which further …

Current drug development strategies devote extensive effort to identifying the molecular
mechanism of action of new drug candidates. Often, if more than one unrelated enzyme or …

Drug discovery and development are long and financially taxing processes. On an average
it takes 12–15 years and costs 1.2 billion USD for successful drug discovery and approval …

Drug repurposing (also known as drug repositioning, drug reprofiling, indication expansion
or indication shift) involves establishing new medical uses for already known drugs …

Drug repurposing refers to the development of existing drugs for new indications. These
drugs may have (i) failed to show efficacy in late stage clinical trials, without safety issues;(ii) …

Drug repurposing holds the potential to bring medications with known safety profiles to new
patient populations. Numerous examples exist for the identification of new indications for …

Drug development is a complex and expensive process that involves extensive research
and testing before a new drug can be approved for use. This has led to a limited availability …

Drug repurposing is a growing purposeful strategy to identify new uses for pharmaceutical
entities at any stage of their commercial or developmental life. Drug repurposing is a …

Drug discovery process is a costly and time-consuming task. An average of 12–15 years is
required for a drug to be approved [1]. The investment required to get it increases …

Drug repurposing refers to finding new indications for existing drugs. The paradigm shift
from traditional drug discovery to drug repurposing is driven by the fact that new drug …