GATA4 is a transcription factor that regulates osteoblast differentiation. However, GATA4 is
expressed at a higher level in mesenchymal stem cells (MSCs) than in osteoblasts …

GATA4 is a transcription factor that is responsible for tissue-specific gene regulation in many
tissues, and more recent studies showed that it is necessary for osteoblast differentiation …

GATA4 is a zinc finger transcription factor that is a pioneer factor in various tissues and
regulates tissue specific gene regulation. In vivo deletion of Gata4 using Cre recombinase …

Osteoblasts play a major role in bone remodeling and are regulated by transcription factors.
GATA4, a zinc finger transcription factor from the GATA family, has an unclear role in …

Osteoblasts are specialized mesenchymal cells that are responsible for bone formation. In
this study, we examine the role of GATA4 in osteoblast differentiation. GATA4 was …

The transcription factor GATA2 is required for expansion and differentiation of hematopoietic
stem cells (HSCs). In mesenchymal stem cells (MSCs), GATA2 blocks adipogenesis, but its …

Gata2 is a zinc finger transcription factor that is important in hematopoiesis and neuronal
development. However, the roles of Gata2 in the mesenchymal lineages are poorly …

Skeletal precursors are mesenchymal in origin and can give rise to distinct sublineages.
Their lineage commitment is modulated by various signaling pathways. The importance of …

Osteoporosis is a disease characterized by low bone mass, leading to an increased risk of
fragility fractures. GATA4 is a zinc‐finger transcription factor that is important in several …

Osteocytes,> 90% of the cells in bone, lie embedded within the mineralized matrix and
coordinate osteoclast and osteoblast activity on bone surfaces by mechanisms still unclear …