Basic mechanisms of diabetic heart disease

RH Ritchie, ED Abel - Circulation Research, 2020 - Am Heart Assoc
Diabetes mellitus predisposes affected individuals to a significant spectrum of
cardiovascular complications, one of the most debilitating in terms of prognosis is heart …

Concurrent diabetes and heart failure: interplay and novel therapeutic approaches

QG Karwi, KL Ho, S Pherwani, EB Ketema… - Cardiovascular …, 2022 - academic.oup.com
Diabetes mellitus increases the risk of developing heart failure, and the co-existence of both
diseases worsens cardiovascular outcomes, hospitalization, and the progression of heart …

[HTML][HTML] Contribution of impaired insulin signaling to the pathogenesis of diabetic cardiomyopathy

M Zamora, JA Villena - International journal of molecular sciences, 2019 - mdpi.com
Diabetic cardiomyopathy (DCM) has emerged as a relevant cause of heart failure among the
diabetic population. Defined as a cardiac dysfunction that develops in diabetic patients …

Diabetic cardiomyopathy, causes and effects

S Boudina, ED Abel - Reviews in Endocrine and Metabolic Disorders, 2010 - Springer
Diabetes is associated with increased incidence of heart failure even after controlling for
coronary artery disease and hypertension. Thus, as diabetic cardiomyopathy has become …

Implications of underlying mechanisms for the recognition and management of diabetic cardiomyopathy

TH Marwick, R Ritchie, JE Shaw, D Kaye - Journal of the American College …, 2018 - jacc.org
Heart failure is a complex clinical syndrome, the incidence and prevalence of which is
increased in diabetes mellitus, pre-diabetes, and obesity. Although this may arise from …

[HTML][HTML] The diabetic cardiomyopathy: the contributing pathophysiological mechanisms

T Salvatore, PC Pafundi, R Galiero, G Albanese… - Frontiers in …, 2021 - frontiersin.org
Individuals with diabetes mellitus (DM) disclose a higher incidence and a poorer prognosis
of heart failure (HF) than non-diabetic people, even in the absence of other HF risk factors …

Diabetic cardiomyopathy and metabolic remodeling of the heart

PK Battiprolu, C Lopez-Crisosto, ZV Wang… - Life sciences, 2013 - Elsevier
The incidence and prevalence of diabetes mellitus are both increasing rapidly in societies
around the globe. The majority of patients with diabetes succumb ultimately to heart disease …

Pathophysiological fundamentals of diabetic cardiomyopathy

X Hu, T Bai, Z Xu, Q Liu, Y Zheng… - Comprehensive …, 2011 - Wiley Online Library
Diabetic cardiomyopathy (DCM) was first recognized more than four decades ago and
occurred independent of cardiovascular diseases or hypertension in both type 1 and type 2 …

[HTML][HTML] Molecular mechanisms of cardiac pathology in diabetes–Experimental insights

U Varma, P Koutsifeli, VL Benson, KM Mellor… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Diabetic cardiomyopathy is a distinct pathology independent of co-morbidities such as
coronary artery disease and hypertension. Diminished glucose uptake due to impaired …

[HTML][HTML] Diabetic cardiomyopathy: Pathophysiology, theories and evidence to date

L Athithan, GS Gulsin, GP McCann… - World journal of …, 2019 - ncbi.nlm.nih.gov
The prevalence of type 2 diabetes (T2D) has increased worldwide and doubled over the last
two decades. It features among the top 10 causes of mortality and morbidity in the world …