Reconfiguration of metabolic fluxes in Pseudomonas putida as a response to sub-lethal oxidative stress
As a frequent inhabitant of sites polluted with toxic chemicals, the soil bacterium and plant-
root colonizer Pseudomonas putida can tolerate high levels of endogenous and exogenous …
root colonizer Pseudomonas putida can tolerate high levels of endogenous and exogenous …
Response of Pseudomonas putida KT2440 to increased NADH and ATP demand
Adenosine phosphate and NAD cofactors play a vital role in the operation of cell
metabolism, and their levels and ratios are carefully regulated in tight ranges. Perturbations …
metabolism, and their levels and ratios are carefully regulated in tight ranges. Perturbations …
The metabolic redox regime of Pseudomonas putida tunes its evolvability toward novel xenobiotic substrates
During evolution of biodegradation pathways for xenobiotic compounds involving Rieske
nonheme iron oxygenases, the transition toward novel substrates is frequently associated …
nonheme iron oxygenases, the transition toward novel substrates is frequently associated …
Metabolic networks to combat oxidative stress in Pseudomonas fluorescens
Oxidative stress is an unavoidable peril that aerobic organisms have to confront. Thus, it is
not surprising that intricate strategies are deployed in an effort to fend the dangers …
not surprising that intricate strategies are deployed in an effort to fend the dangers …
From dirt to industrial applications: Pseudomonas putida as a synthetic biology chassis for hosting harsh biochemical reactions
Highlights•SynBio needs chassis with superior genetic, biochemical, and physiological
traits.•Environmental bacteria are endowed with many advantageous metabolic properties.• …
traits.•Environmental bacteria are endowed with many advantageous metabolic properties.• …
[HTML][HTML] Pseudomonas putida as a functional chassis for industrial biocatalysis: from native biochemistry to trans-metabolism
PI Nikel, V de Lorenzo - Metabolic engineering, 2018 - Elsevier
The itinerary followed by Pseudomonas putida from being a soil-dweller and plant colonizer
bacterium to become a flexible and engineer-able platform for metabolic engineering stems …
bacterium to become a flexible and engineer-able platform for metabolic engineering stems …
The Entner–Doudoroff pathway empowers Pseudomonas putida KT2440 with a high tolerance to oxidative stress
Glucose catabolism of P seudomonas putida is carried out exclusively through the E ntner–
D oudoroff (ED) pathway due to the absence of 6‐phosphofructokinase. In order to activate …
D oudoroff (ED) pathway due to the absence of 6‐phosphofructokinase. In order to activate …
Pseudomonas putida KT2440 is naturally endowed to withstand industrial‐scale stress conditions
A Ankenbauer, RA Schäfer, SC Viegas… - Microbial …, 2020 - Wiley Online Library
Pseudomonas putida is recognized as a very promising strain for industrial application due
to its high redox capacity and frequently observed tolerance towards organic solvents. In this …
to its high redox capacity and frequently observed tolerance towards organic solvents. In this …
Metabolic response of Pseudomonas putida during redox biocatalysis in the presence of a second octanol phase
A key limitation of whole‐cell redox biocatalysis for the production of valuable, specifically
functionalized products is substrate/product toxicity, which can potentially be overcome by …
functionalized products is substrate/product toxicity, which can potentially be overcome by …
The revisited genome of Pseudomonas putida KT2440 enlightens its value as a robust metabolic chassis
E Belda, RGA Van Heck… - Environmental …, 2016 - Wiley Online Library
By the time the complete genome sequence of the soil bacterium Pseudomonas putida
KT2440 was published in 2002 (Nelson et al.,) this bacterium was considered a potential …
KT2440 was published in 2002 (Nelson et al.,) this bacterium was considered a potential …