Composition of the gut microbiota modulates the severity of malaria

NF Villarino, GR LeCleir, JE Denny… - Proceedings of the …, 2016 - National Acad Sciences
Plasmodium infections result in clinical presentations that range from asymptomatic to
severe malaria, resulting in∼ 1 million deaths annually. Despite this toll on humanity, the …

Inflammation-associated alterations to the intestinal microbiota reduce colonization resistance against non-typhoidal Salmonella during concurrent malaria parasite …

JP Mooney, KL Lokken, MX Byndloss, MD George… - Scientific reports, 2015 - nature.com
Childhood malaria is a risk factor for disseminated infections with non-typhoidal Salmonella
(NTS) in sub-Saharan Africa. While hemolytic anemia and an altered cytokine environment …

Stool microbiota composition is associated with the prospective risk of Plasmodium falciparum infection

S Yooseph, EF Kirkness, TM Tran, DM Harkins… - BMC genomics, 2015 - Springer
Background In humans it is unknown if the composition of the gut microbiota alters the risk of
Plasmodium falciparum infection or the risk of developing febrile malaria once P. falciparum …

[HTML][HTML] Plasmodium berghei ANKA causes intestinal malaria associated with dysbiosis

T Taniguchi, E Miyauchi, S Nakamura, M Hirai… - Scientific reports, 2015 - nature.com
Gastrointestinal symptoms, such as abdominal pain and diarrhea, are frequently observed in
patients with Plasmodium falciparum malaria. However, the correlation between malaria …

Diet–microbiome–disease: Investigating diet's influence on infectious disease resistance through alteration of the gut microbiome

EV Harris, JC de Roode, NM Gerardo - PLoS pathogens, 2019 - journals.plos.org
Abiotic and biotic factors can affect host resistance to parasites. Host diet and host gut
microbiomes are two increasingly recognized factors influencing disease resistance. In …

[HTML][HTML] Gut microbiota elicits a protective immune response against malaria transmission

B Yilmaz, S Portugal, TM Tran, R Gozzelino, S Ramos… - Cell, 2014 - cell.com
Glycosylation processes are under high natural selection pressure, presumably because
these can modulate resistance to infection. Here, we asked whether inactivation of the UDP …

Implication of the mosquito midgut microbiota in the defense against malaria parasites

Y Dong, F Manfredini, G Dimopoulos - PLoS pathogens, 2009 - journals.plos.org
Malaria-transmitting mosquitoes are continuously exposed to microbes, including their
midgut microbiota. This naturally acquired microbial flora can modulate the mosquito's …

Parasitic protozoa and interactions with the host intestinal microbiota

SL Burgess, CA Gilchrist, TC Lynn… - Infection and …, 2017 - Am Soc Microbiol
Parasitic protozoan infections represent a major health burden in the developing world and
contribute significantly to morbidity and mortality. These infections are often associated with …

The microbiota and helminths: sharing the same niche in the human host

L Glendinning, N Nausch, A Free, DW Taylor… - Parasitology, 2014 - cambridge.org
Human gastrointestinal bacteria often share their environment with parasitic worms, allowing
physical and physiological interaction between the two groups. Such associations have the …

The interplay of host microbiota and parasitic protozoans at mucosal interfaces: implications for the outcomes of infections and diseases

AK Bär, N Phukan, J Pinheiro… - PLoS neglected …, 2015 - journals.plos.org
Infections by parasitic protozoans are largely neglected, despite threatening millions of
people, particularly in developing countries. With descriptions of the microbiota in humans, a …