Background Fat grafting, as a standard treatment for numerous soft tissue defects, remains
unpredictable and technique-dependent. Human adipose-derived stem cells (hADSCs) are …

Background Modified cell-based angiogenic therapy has become a promising novel strategy
for ischemic heart and limb diseases. Most studies focused on myoblast, endothelial cell …

Importance of the field: Several lines of evidence suggest that VEGF is a key regulator of the
paracrine effects of adipose-derived stem cells (ASCs), but the mechanism of action remains …

Human adipose tissue-derived stem cells (ADSCs) are an attractive multipotent stem cell
source with therapeutic applicability across diverse fields for the repair and regeneration of …

Background: The efficacy of autologous fat transplantation is reduced by fat absorption and
fibrosis due to fat necrosis. Enhanced transplant neovascularization early after …

Therapeutic angiogenesis is an important means to salvage tissues against severe ischemic
diseases in patients with no option for other vascular intervention. A number of recent …

Mesenchymal stem cells (MSCs) hold tremendous potential for therapeutic use in stem cell-
based gene therapy. Ex vivo genetic modification of MSCs with beneficial genes of interest …

Lentiviral transduction of human mesenchymal stem cells (MSCs) induces long-term
transgene expression and holds great promise for multiple gene therapy applications …

Obesity is a highly prevalent condition often associated with dysfunctional adipose tissue.
Stem cell-based therapies have become a promising tool for therapeutic intervention in the …

Introduction Cell therapy using adipose-derived stromal cells (ADSC) is an intensively
developing approach to promote angiogenesis and regeneration. Administration technique …