Combined topical and systemic administration with human adipose-derived mesenchymal stem cells (hADSC) and hADSC-derived exosomes markedly promoted …

Y Zhou, B Zhao, XL Zhang, Y Lu, ST Lu… - Stem cell research & …, 2021 - Springer
Background Cutaneous wound healing and regeneration have become a recognized health
challenge in the world, which causes severe damage to the mental and physical health of …

Exosomes derived from human adipose mensenchymal stem cells accelerates cutaneous wound healing via optimizing the characteristics of fibroblasts

LI Hu, J Wang, X Zhou, Z Xiong, J Zhao, R Yu… - Scientific reports, 2016 - nature.com
Prolonged healing and scar formation are two major challenges in the treatment of soft
tissue trauma. Adipose mesenchymal stem cells (ASCs) play an important role in tissue …

Cell-free therapy based on adipose tissue stem cell-derived exosomes promotes wound healing via the PI3K/Akt signaling pathway

W Zhang, X Bai, B Zhao, Y Li, Y Zhang, Z Li… - Experimental cell …, 2018 - Elsevier
Introduction Adipose tissue-derived stem cells (ADSCs) have been shown to enhance
wound healing via their paracrine function. Exosomes, as one of the most important …

Human adipose-derived mesenchymal stem cells-derived exosomes encapsulated in pluronic F127 hydrogel promote wound healing and regeneration

Y Zhou, XL Zhang, ST Lu, NY Zhang, HJ Zhang… - Stem cell research & …, 2022 - Springer
Background Large area skin trauma has always been a great challenge for both patients
and clinicians. Exosomes originating from human adipose-derived mesenchymal stem cells …

Human exosomes accelerate cutaneous wound healing by promoting collagen synthesis in a diabetic mouse model

B Zhao, X Zhang, Y Zhang, Y Lu, W Zhang… - Stem Cells and …, 2021 - liebertpub.com
Chronic wounds including diabetic foot ulcers are clinical emergencies that need careful
management. Exosomes from human adipose-derived mesenchymal stem cells (hADSCs …

Exosomes from adipose‐derived stem cells and application to skin wound healing

Y An, S Lin, X Tan, S Zhu, F Nie, Y Zhen, L Gu… - Cell …, 2021 - Wiley Online Library
Skin wound healing is an intractable problem that represents an urgent clinical need. To
solve this problem, a large number of studies have focused on the use of exosomes (EXOs) …

Adipose tissue-derived mesenchymal stem cell-derived exosomes promote wound healing and tissue regeneration

JH Lee, YJ Won, H Kim, M Choi, E Lee… - International Journal of …, 2023 - mdpi.com
Wound healing is a complex process involving cell proliferation, migration, and extracellular
matrix (ECM) remodeling. Extracellular vesicles (EVs) or exosomes derived from adipose …

[HTML][HTML] Mesenchymal stem cell-derived exosomes: A novel and potential remedy for cutaneous wound healing and regeneration

JC Hu, CX Zheng, BD Sui, WJ Liu… - World Journal of Stem …, 2022 - ncbi.nlm.nih.gov
Poor healing of cutaneous wounds is a common medical problem in the field of
traumatology. Due to the intricate pathophysiological processes of wound healing, the use of …

Adipose mesenchymal stem cell-derived exosomes promote wound healing through the WNT/β-catenin signaling pathway in dermal fibroblasts

C Li, Y An, Y Sun, F Yang, Q Xu, Z Wang - Stem Cell Reviews and Reports, 2022 - Springer
The differentiation, migration, and proliferation of skin fibroblasts are identified as key factors
in cutaneous wound healing. Adipose-derived mesenchymal stem cells (ADMSCs) and their …

Exosomes released from educated mesenchymal stem cells accelerate cutaneous wound healing via promoting angiogenesis

X Qiu, J Liu, C Zheng, Y Su, L Bao, B Zhu… - Cell …, 2020 - Wiley Online Library
Objectives Skin serves as the major interface between the external environment and body
which is liable to many kinds of injuries. Mesenchymal stem cell (MSC) therapy has been …