Differential metal sensing and metal‐dependent degradation of the broad spectrum root metal transporter IRT1

J Spielmann, V Cointry, F Devime, S Ravanel… - The Plant …, 2022 - Wiley Online Library
Iron is an essential micronutrient for plant growth and development. Under low iron
conditions, Arabidopsis plants take up soil iron using the root iron transporter IRT1. In …

Expression of the IRT1 metal transporter is controlled by metals at the levels of transcript and protein accumulation

EL Connolly, JP Fett, ML Guerinot - The Plant Cell, 2002 - academic.oup.com
Iron, an essential nutrient, is not readily available to plants because of its low solubility. In
addition, iron is toxic in excess, catalyzing the formation of hydroxyl radicals that can …

Metal sensing by the IRT1 transporter-receptor orchestrates its own degradation and plant metal nutrition

G Dubeaux, J Neveu, E Zelazny, G Vert - Molecular cell, 2018 - cell.com
Plant roots forage the soil for iron, the concentration of which can be dramatically lower than
those needed for growth. Soil iron uptake uses the broad metal spectrum IRT1 transporter …

Regulation of iron uptake by IRT1: endocytosis pulls the trigger

E Zelazny, G Vert - Molecular plant, 2015 - cell.com
The past two decades of research on plant iron nutrition have completed the casting of the
major transporters involved in iron uptake from the soil, long-distance transport, and …

Iron-induced turnover of the Arabidopsis IRON-REGULATED TRANSPORTER1 metal transporter requires lysine residues

L Kerkeb, I Mukherjee, I Chatterjee, B Lahner… - Plant …, 2008 - academic.oup.com
Iron is an essential micronutrient but is toxic if accumulated at high levels. Thus, iron uptake
and distribution in plants are controlled by precise regulatory mechanisms. IRON …

IRT1, an Arabidopsis transporter essential for iron uptake from the soil and for plant growth

G Vert, N Grotz, F Dédaldéchamp, F Gaymard… - The plant …, 2002 - academic.oup.com
Plants are the principal source of iron in most diets, yet iron availability often limits plant
growth. In response to iron deficiency, Arabidopsis roots induce the expression of the …

Dynamic control of the high-affinity iron uptake complex in root epidermal cells

A Martín-Barranco, J Spielmann, G Dubeaux… - Plant …, 2020 - academic.oup.com
In plants, iron uptake from the soil is tightly regulated to ensure optimal growth and
development. Iron absorption in Arabidopsis root epidermal cells requires the IRT1 …

Monoubiquitin-dependent endocytosis of the iron-regulated transporter 1 (IRT1) transporter controls iron uptake in plants

M Barberon, E Zelazny, S Robert… - Proceedings of the …, 2011 - National Acad Sciences
Plants take up iron from the soil using the IRON-REGULATED TRANSPORTER 1 (IRT1)
high-affinity iron transporter at the root surface. Sophisticated regulatory mechanisms allow …

Birth, life and death of the Arabidopsis IRT1 iron transporter: the role of close friends and foes

A Abuzeineh, G Vert, E Zelazny - Planta, 2022 - Springer
Main conclusion IRT1 intracellular dynamics and function are finely controlled through
protein–protein interactions. Abstract In plants, iron uptake from the soil is tightly regulated to …

Arabidopsis IRT2 gene encodes a root‐periphery iron transporter

G Vert, JF Briat, C Curie - The Plant Journal, 2001 - Wiley Online Library
Iron uptake from the soil is a tightly controlled process in plant roots, involving specialized
transporters. One such transporter, IRT1, was identified in Arabidopsis thaliana and shown …