Opportunistic screening at abdominal CT: use of automated body composition biomarkers for added cardiometabolic value

PJ Pickhardt, PM Graffy, AA Perez, MG Lubner… - Radiographics, 2021 - pubs.rsna.org
Abdominal CT is a frequently performed imaging examination for a wide variety of clinical
indications. In addition to the immediate reason for scanning, each CT examination contains …

Value-added opportunistic CT screening: state of the art

PJ Pickhardt - Radiology, 2022 - pubs.rsna.org
Opportunistic CT screening leverages robust imaging data embedded within abdominal and
thoracic scans that are generally unrelated to the specific clinical indication and have …

Abdominal CT body composition thresholds using automated AI tools for predicting 10-year adverse outcomes

MH Lee, R Zea, JW Garrett, PM Graffy, RM Summers… - Radiology, 2022 - pubs.rsna.org
Background CT-based body composition measures derived from fully automated artificial
intelligence tools are promising for opportunistic screening. However, body composition …

Fully automated CT imaging biomarkers of bone, muscle, and fat: correcting for the effect of intravenous contrast

AA Perez, PJ Pickhardt, DC Elton, V Sandfort… - Abdominal …, 2021 - Springer
Purpose Fully automated CT-based algorithms for quantifying bone, muscle, and fat have
been validated for unenhanced abdominal scans. The purpose of this study was to …

Utilizing fully automated abdominal CT–based biomarkers for opportunistic screening for metabolic syndrome in adults without symptoms

PJ Pickhardt, PM Graffy, R Zea, SJ Lee… - American Journal of …, 2021 - Am Roentgen Ray Soc
Please see the Editorial Comment by Orlando Catalano discussing this article. To listen to
the podcast associated with this article, please select one of the following: iTunes, Google …

AI-based opportunistic CT screening of incidental cardiovascular disease, osteoporosis, and sarcopenia: cost-effectiveness analysis

PJ Pickhardt, L Correale, C Hassan - Abdominal Radiology, 2023 - Springer
Purpose To assess the cost-effectiveness and clinical efficacy of AI-assisted abdominal CT-
based opportunistic screening for atherosclerotic cardiovascular (CV) disease, osteoporosis …

Fully automated segmentation and quantification of visceral and subcutaneous fat at abdominal CT: application to a longitudinal adult screening cohort

SJ Lee, J Liu, J Yao, A Kanarek… - The British journal of …, 2018 - academic.oup.com
Objective: To investigate a fully automated CT-based adiposity tool, applying it to a
longitudinal adult screening cohort. Methods: A validated automated adipose tissue …

Opportunistic Screening: Radiology Scientific Expert Panel

PJ Pickhardt, RM Summers, JW Garrett, A Krishnaraj… - Radiology, 2023 - pubs.rsna.org
Radiologic tests often contain rich imaging data not relevant to the clinical indication.
Opportunistic screening refers to the practice of systematically leveraging these incidental …

Automated CT biomarkers for opportunistic prediction of future cardiovascular events and mortality in an asymptomatic screening population: a retrospective cohort …

PJ Pickhardt, PM Graffy, R Zea, SJ Lee, J Liu… - The Lancet Digital …, 2020 - thelancet.com
Background Body CT scans are frequently done for a wide range of clinical indications, but
potentially valuable biometric information typically goes unused. We aimed to compare the …

Population-scale CT-based body composition analysis of a large outpatient population using deep learning to derive age-, sex-, and race-specific reference curves

K Magudia, CP Bridge, CP Bay, A Babic, FJ Fintelmann… - Radiology, 2021 - pubs.rsna.org
Background Although CT-based body composition (BC) metrics may inform disease risk and
outcomes, obtaining these metrics has been too resource intensive for large-scale use …