Oxytocin reduces cigarette consumption in daily smokers

K Van Hedger, MJ Kushner, R Lee… - Nicotine and Tobacco …, 2019 - academic.oup.com
Introduction Despite widespread knowledge of the dangers of cigarette consumption,
smoking continues to be a public health concern. One compound that has shown potential …

Intranasal oxytocin dampens cue-elicited cigarette craving in daily smokers: a pilot study

MA Miller, A Bershad, AC King, R Lee… - Behavioural …, 2016 - journals.lww.com
Despite moderate success with pharmacological and behavioral treatments, smoking
relapse rates remain high, and many smokers report that smoking cues lead to relapse …

Effects of intranasal oxytocin on stress-induced cigarette craving in daily smokers

K Van Hedger, AK Bershad, R Lee… - Nicotine and Tobacco …, 2020 - academic.oup.com
Background Cigarette smoking is a well-known public health concern, and there is an urgent
need to develop new treatments to reduce smoking or facilitate abstinence. One factor that is …

Oxytocin as a potential mediator and modulator of drug addiction

Z Sarnyai - Addiction Biology, 2011 - researchonline.jcu.edu.au
[Extract] Oxytocin, a nine amino acid neuropeptide, first discovered by Sir Heury Dale in
1906, is a potent modulator of a variety of brain functions including emotions, mood, social …

Effects of intranasal oxytocin on cigarette withdrawal and smoking in the laboratory: Differences by sex and social functioning traits.

KA Simpson, MD Stone, AM Leventhal… - Experimental and …, 2024 - psycnet.apa.org
Intranasal oxytocin (INOT) has received attention as a treatment for substance use disorders
including tobacco dependence. However, it is unclear whether INOT-related effects differ by …

Intranasal oxytocin does not modulate responses to alcohol in social drinkers

A Vena, A King, R Lee, H de Wit - Alcoholism: Clinical and …, 2018 - Wiley Online Library
Background Preclinical and clinical evidence suggest that the neuropeptide oxytocin may be
of value in treating alcohol use disorder, by either reducing the rewarding effects of alcohol …

Oxytocin, tolerance, and the dark side of addiction

CA Pedersen - International review of neurobiology, 2017 - Elsevier
Substance use disorders blight the lives of millions of people and inflict a heavy financial
burden on society. There is a compelling need for new pharmacological treatments as …

Effects of oxytocin on nicotine withdrawal in rats

KE Manbeck, D Shelley, CE Schmidt… - … Biochemistry and Behavior, 2014 - Elsevier
Abstract Development of medications that attenuate symptoms of nicotine withdrawal may
be useful for facilitating smoking cessation. The neuropeptide oxytocin (OXY) decreases …

Oxytocin and addiction: potential glutamatergic mechanisms

M Sundar, D Patel, Z Young, KC Leong - International journal of …, 2021 - mdpi.com
Recently, oxytocin (OXT) has been investigated for its potential therapeutic role in addiction.
OXT has been found to diminish various drug-seeking and drug-induced behaviors …

Oxytocin and the mechanisms of alcohol dependence

T Faehrmann, G Zernig, S Mechtcheriakov - neuropsychiatrie, 2018 - Springer
One of the crucial purposes of treating alcohol-dependent patients is to enhance their ability
to stay abstinent after detoxification therapy. Anxiety and stress vulnerability are the main …