Blockade of β-adrenergic receptors by propranolol disrupts reconsolidation of drug memory and attenuates heroin seeking
L Chen, S Huang, C Yang, F Wu, Q Zheng… - Frontiers in …, 2021 - frontiersin.org
Persistent traces of drug reward memories contribute to intense craving and often trigger
relapse. A number of pharmacological interventions on drug-associated memories have …
relapse. A number of pharmacological interventions on drug-associated memories have …
Reactivating addiction-related memories under propranolol to reduce craving: a pilot randomized controlled trial
Background The reconsolidation blocker propranolol abolishes alcohol and drug-seeking
behavior in rodents and attenuates conditioned emotional responses to drug-cues in …
behavior in rodents and attenuates conditioned emotional responses to drug-cues in …
Inhibition of β-adrenergic receptors induces a persistent deficit in retrieval of a cocaine-associated memory providing protection against reinstatement
Drug-seeking behavior is maintained by encounters with drug-associated cues. Preventing
retrieval of drug-associated memories that these cues provoke would therefore limit relapse …
retrieval of drug-associated memories that these cues provoke would therefore limit relapse …
Modulating reconsolidation and extinction to regulate drug reward memory
Drug addiction is an aberrant memory that shares the same memory processes as other
memories. Brief exposure to drug‐associated cues could result in reconsolidation, a …
memories. Brief exposure to drug‐associated cues could result in reconsolidation, a …
Effects of β-adrenergic receptor blockade on drug-related memory reconsolidation in abstinent heroin addicts
LY Zhao, LL Sun, J Shi, P Li, Y Zhang, L Lu - Drug and alcohol …, 2011 - Elsevier
RATIONALE AND OBJECTIVE: The reactivation of a consolidated memory can return it to a
labile state, a process referred to as reconsolidation. A previous study showed that oral …
labile state, a process referred to as reconsolidation. A previous study showed that oral …
Inhibition of hippocampal β-adrenergic receptors impairs retrieval but not reconsolidation of cocaine-associated memory and prevents subsequent reinstatement
Retrieval of drug-associated memories is critical for maintaining addictive behaviors, as
presentation of drug-associated cues can elicit drug seeking and relapse. Recently, we and …
presentation of drug-associated cues can elicit drug seeking and relapse. Recently, we and …
Differential effects of propranolol on conditioned hyperactivity and locomotor sensitization induced by morphine in rats
S Wei, X Li - Scientific Reports, 2014 - nature.com
According to memory reconsolidation theory, when long-term memory is reactivated by
relevant clues, the memory traces become labile, which can be altered by pharmacological …
relevant clues, the memory traces become labile, which can be altered by pharmacological …
Post-retrieval propranolol treatment does not modulate reconsolidation or extinction of ethanol-induced conditioned place preference
L Font, CL Cunningham - Pharmacology Biochemistry and Behavior, 2012 - Elsevier
The reconsolidation hypothesis posits that established emotional memories, when
reactivated, become labile and susceptible to disruption. Post-retrieval injection of …
reactivated, become labile and susceptible to disruption. Post-retrieval injection of …
Disruption of long-term alcohol-related memory reconsolidation: role of β-adrenoceptors and NMDA receptors
JA Wouda, L Diergaarde, D Riga, Y Mourik… - Frontiers in behavioral …, 2010 - frontiersin.org
Disrupting reconsolidation of drug-related memories may be effective in reducing the
incidence of relapse. In the current study we examine whether alcohol-related memories are …
incidence of relapse. In the current study we examine whether alcohol-related memories are …
β1-adrenoceptor in the central amygdala is required for unconditioned stimulus-induced drug memory reconsolidation
H Zhu, Y Zhou, Z Liu, X Chen, Y Li… - International Journal of …, 2018 - academic.oup.com
Background Drug memories become labile and reconsolidated after retrieval by
presentation of environmental cues (conditioned stimulus) or drugs (unconditioned …
presentation of environmental cues (conditioned stimulus) or drugs (unconditioned …