Background: Secondary hyperparathyroidism (SHPT) is an adaptive process that develops
in response to declining kidney function, impaired phosphate excretion, and failure to …

Introduction: Secondary hyperparathyroidism (SHPT) is a common complication associated
with morbidity and mortality among hemodialysis (HD) patients. Objectives: The current …

Background Secondary hyperparathyroidism (SHPT) is a common complication of chronic
kidney disease (CKD) patients on dialysis, associated with increased cardiovascular …

Cinacalcet, a novel calcimimetic compound, is effective in reducing parathyroid hormone
(PTH) levels in approximately 70% of patients with secondary hyperparathyroidism …

The objective of this study was to determine the impact of calcium sensing receptor (CASR)
A990G genetic polymorphism on parathyroid hormone (PTH) lowering response to …

Methods: Frequency of CASR rs7652589 nucleotide variants in HD patients (n= 1162) was
compared to that of healthy controls (n= 918) to exclude uremia-related association. HD …

Background Secondary hyperparathyroidism (SHPT) is one of the major risk factors of
morbidity and mortality in end-stage renal disease. Cinacalcet effectively controls SHPT …

Objective To evaluate correlations between polymorphisms of calcium-sensing receptor
(CASR) gene [A986S (rs1081725), R990G (rs1042636) and Q1011E (rs1801726)] and the …

Abstract Nephrolithiasis, secondary hyperparathyroidism (sHPT), and cardiovascular
complications are associated with disturbances in Ca handling and contribute to …

Results There were modest associations of CASR SNPs with increased baseline serum
parathyroid hormone and bone alkaline phosphatase primarily with the minor allele in the …