Spexin status in relation to obesity and its related comorbidities: a systematic review

M Behrooz, E Vaghef-Mehrabany, V Maleki… - Journal of Diabetes & …, 2020 - Springer
Purpose Spexin, a novel 14-amino acid peptide, has multiple physiological functions. The
purpose of this paper was to systematically evaluate the current literature on the role of …

Spexin as an indicator of beneficial effects of exercise in human obesity and diabetes

A Khadir, S Kavalakatt, D Madhu, S Devarajan… - Scientific reports, 2020 - nature.com
Spexin is a novel neuropeptide playing an emerging role in metabolic diseases such as
obesity and diabetes via involvement in energy homeostasis and food intake. The present …

Circulating spexin levels negatively correlate with age, BMI, fasting glucose, and triglycerides in healthy adult women

C Lin, T Huang, L Zhao, LLD Zhong… - Journal of the …, 2018 - academic.oup.com
Context Spexin is a newly identified neuropeptide that is involved in satiety control, glucose,
and lipids metabolism. It has also been related to human diseases, such as obesity and type …

Circulating spexin is associated with body mass index and fat mass but not with physical activity and psychological parameters in women across a broad body weight …

M Suhs, A Stengel, A Rudolph, S Schaper… - Journal of Clinical …, 2022 - mdpi.com
Spexin (SPX) is a novel, widely expressed peptide, with anorexigenic effects demonstrated
in animal models and negatively correlated with body mass index (BMI) in humans. It …

Spexin levels are associated with metabolic syndrome components

NM Al-Daghri, A Alenad, H Al-Hazmi, OE Amer… - Disease …, 2018 - Wiley Online Library
Background. Spexin (SPX) is a novel peptide that is implicated in obesity and related energy
homeostasis in animals and adult humans. Little is known about its role in adults' overall …

Novel insights on the role of spexin as a biomarker of obesity and related cardiometabolic disease

S Kumar, RT Mankowski, SD Anton… - International Journal of …, 2021 - nature.com
Abstract Spexin (SPX) is a 14-amino acid neuropeptide, discovered recently using
bioinformatic techniques. It is encoded by the Ch12: orf39 gene that is widely expressed in …

Decreased circulating levels of spexin in obese children

S Kumar, J Hossain, N Nader, R Aguirre… - The Journal of …, 2016 - academic.oup.com
Context: Spexin is a novel peptide that is implicated in obesity and related energy
homeostasis in animals and adult humans. Little is known about its role in children …

Different spexin level in obese vs normal weight children and its relationship with obesity related risk factors

M Behrooz, E Vaghef-Mehrabany… - Nutrition, Metabolism and …, 2020 - Elsevier
Background and aims Spexin (SPX) is a novel peptide recently discovered as an important
regulatory adipokine in obesity and related metabolic diseases. The aim of the current study …

[HTML][HTML] Decreased spexin levels in patients with type 1 and type 2 diabetes

A Karaca, F Bakar-Ates, N Ersoz-Gulcelik - Medical Principles and …, 2019 - karger.com
Background/Aims: Spexin is a novel peptide which has a potential role as a biomarker of
insulin resistance, diabetes, and obesity. Our aim was to measure spexin levels in lean type …

[HTML][HTML] Novel hypothalamic pathways for metabolic effects of spexin

P Fang, Y She, M Yu, J Yan, X Yu, J Zhao, Y Jin… - Pharmacological …, 2024 - Elsevier
One of the main underlying etiologies of type 2 diabetes (T2DM) is insulin resistance, which
is most frequently caused by obesity. Notably, the deregulation of adipokine secretion from …