Mitochondria are central organelles in the homeostasis of the cardiovascular system via the
integration of several physiological processes, such as ATP generation via oxidative …

Mitochondria has an essential role in myocardial tissue homeostasis; thus deterioration in
mitochondrial function eventually leads to cardiomyocyte and endothelial cell death and …

Introduction: One target of toxicity caused by cardiac drugs is the mitochondrion. This review
focuses on the mitochondrion-toxic effects of cardiac drugs and the extent to which …

Cardiovascular diseases (CVDs) are serious problems that threaten public health and are
responsible for nearly one-third of global deaths. Mitochondrial dysfunction is accountable …

The critical role of mitochondria in cardiomyocyte survival and death has become an exciting
field of research in cardiac biology. Indeed, it is accepted that mitochondrial dysfunction …

Mitochondria, responsible for energy metabolism within the cell, act as signaling organelles.
Mitochondrial dysfunction may lead to cell death and oxidative stress and may disturb …

Background: Certain therapeutic drugs used in medical practice may trigger mitochondrial
toxicity leading to a wide range of clinical symptoms including deafness, neuropathy …

Mitochondria are organelles that play a pivotal role in the production of energy in cells, and
vital to the maintenance of cellular homeostasis due to the regulation of many biochemical …

Mitochondria are one of the major sites for the generation of reactive oxygen species (ROS)
as an undesirable side product of oxidative energy metabolism. Damaged mitochondria can …

Mitochondrial malfunction is related to aging and to the onset of many diseases, such as
obesity/diabetes, cancer, and cardiovascular and neurodegenerative diseases. The …