[HTML][HTML] A leaky gut dysregulates gene networks in the brain associated with immune activation, oxidative stress, and myelination in a mouse model of colitis
JS Boles, ME Krueger, JE Jernigan, CL Cole… - Brain, Behavior, and …, 2024 - Elsevier
The gut and brain are increasingly linked in human disease, with neuropsychiatric
conditions classically attributed to the brain showing an involvement of the intestine and …
conditions classically attributed to the brain showing an involvement of the intestine and …
[HTML][HTML] The gut–immune–brain axis: an important route for neuropsychiatric morbidity in inflammatory bowel disease
Inflammatory bowel disease (IBD) comprises Crohn's disease (CD) and ulcerative colitis
(UC) and is associated with neuropsychiatric symptoms like anxiety and depression. Both …
(UC) and is associated with neuropsychiatric symptoms like anxiety and depression. Both …
[HTML][HTML] The gut-brain axis in inflammatory bowel disease—current and future perspectives
The gut–brain axis is a bidirectional communication system driven by neural, hormonal,
metabolic, immunological, and microbial signals. Signaling events from the gut can …
metabolic, immunological, and microbial signals. Signaling events from the gut can …
Advances in Brain-Gut-Microbiome Interactions: A Comprehensive Update on Signaling Mechanisms, Disorders, and Therapeutic Implications
The complex, bidirectional interactions between the brain, the gut and the gut microbes are
best referred to as the Brain Gut Microbiome system. Animal and clinical studies have …
best referred to as the Brain Gut Microbiome system. Animal and clinical studies have …
[HTML][HTML] Impact of intestinal disorders on central and peripheral nervous system diseases
Brain injuries and neurological diseases have a significant impact on the gut microbiome
and the gut barrier. Reciprocally, gut disorders, such as Inflammatory Bowel Syndromes …
and the gut barrier. Reciprocally, gut disorders, such as Inflammatory Bowel Syndromes …
The enteric nervous system relays psychological stress to intestinal inflammation
KM Schneider, N Blank, Y Alvarez, K Thum… - Cell, 2023 - cell.com
Mental health profoundly impacts inflammatory responses in the body. This is particularly
apparent in inflammatory bowel disease (IBD), in which psychological stress is associated …
apparent in inflammatory bowel disease (IBD), in which psychological stress is associated …
[HTML][HTML] The neurobiology of irritable bowel syndrome
Irritable bowel syndrome (IBS) is the most prevalent disorder of brain-gut interactions that
affects between 5 and 10% of the general population worldwide. The current symptom …
affects between 5 and 10% of the general population worldwide. The current symptom …
[HTML][HTML] The brain-gut-microbiome axis
CR Martin, V Osadchiy, A Kalani, EA Mayer - Cellular and molecular …, 2018 - Elsevier
Preclinical and clinical studies have shown bidirectional interactions within the brain-gut-
microbiome axis. Gut microbes communicate to the central nervous system through at least …
microbiome axis. Gut microbes communicate to the central nervous system through at least …
[HTML][HTML] From Gut to Brain: Uncovering Potential Serum Biomarkers Connecting Inflammatory Bowel Diseases to Neurodegenerative Diseases
OF Sarb, AD Sarb, M Iacobescu, IM Vlad… - International Journal of …, 2024 - mdpi.com
Inflammatory bowel diseases (IBDs) are characterized by chronic gastrointestinal
inflammation due to abnormal immune responses to gut microflora. The gut–brain axis is …
inflammation due to abnormal immune responses to gut microflora. The gut–brain axis is …
The Emerging Role of the Gut–Brain–Microbiota Axis in Neurodevelopmental Disorders
Autism spectrum disorder (ASD; autism) is a prevalent neurodevelopmental disorder
associated with changes in gut-brain axis communication. Gastrointestinal (GI) symptoms …
associated with changes in gut-brain axis communication. Gastrointestinal (GI) symptoms …