The term nanodisk refers to a discrete type of nanoparticle comprised of a bilayer forming
lipid, a scaffold protein, and an integrated bioactive agent. Nanodisks are organized as a …

Liposomes are artificially prepared vesicular lipid nanoparticles with a bilayer structure,
resembling cell membrane. Their ability to encapsulate various molecules along with …

Nowadays, there has been an increasing utilization of nanomedicines for disease treatment.
Nanodiscs (NDs) have emerged as a novel platform technology that garners significant …

Membrane proteins are involved in numerous vital biological processes, including transport,
signal transduction and the enzymes in a variety of metabolic pathways. Integral membrane …

Objectives NanoDisk–amphotericin B (ND-AMB) is a protein-phospholipid bioparticle
containing a “super aggregate” form of antifungal AMB. While lipid-based formulations of …

For decades, clinicians have used liposomes, self-assembled lipid vesicles, as nanoscale
systems to deliver encapsulated anthracycline molecules for cancer treatment. The more …

Nanodiscs are discoidal particles with a planar phospholipid bilayer enwrapped by proteins
such as apolipoprotein AI. Nanodiscs have been widely used for analyzing structures and …

Abstract Development of synthetic bioarchitectures to improve our understanding of
biological systems and produce biosynthetic models with new functions has attracted …

Membrane proteins are central to biological signaling pathways, regulating transfer of
information and energy across cell membranes. They compose roughly 30% of the human …

High-density lipoprotein (HDL) plays a fundamental role in the Reverse Cholesterol
Transport pathway. Prior to maturation, nascent HDL exist as disk-shaped phospholipid …