Pancreatic adenocarcinoma (PDAC) originates in the glandular compartment of the exocrine
pancreas. Histologically, PDAC tumors are characterized by a parenchyma that is …

Pancreatic ductal adenocarcinoma (PDAC) is among the most lethal malignancies and is
characterized by a unique tumor microenvironment (TME) consisting of an abundant stromal …

Pancreatic adenocarcinoma is a highly lethal disease that is histologically characterized by
a dense desmoplastic reaction (DR) surrounding malignant epithelial cells. The DR is …

Pancreatic ductal adenocarcinoma (PDAC) features a prominent stromal microenvironment
with remarkable cellular and spatial heterogeneity that meaningfully impacts disease …

Pancreatic ductal adenocarcinoma (PDA) is a common and lethal malignancy resulting in
more than 250,000 deaths per year worldwide. Despite extensive efforts, cytotoxic and …

Pancreatic ductal adenocarcinoma (PDAC) causes annually well over 400,000 deaths world-
wide and remains one of the major unresolved health problems. This exocrine pancreatic …

Pancreatic ductal adenocarcinoma (PDAC) is the most prevalent form of pancreatic cancer
and carries the worst prognosis of all common cancers. Five-year survival rates have not …

Pancreatic ductal adenocarcinoma remains one of the most lethal solid tumors due to its
local aggressiveness and metastatic potential, with a 5-year survival rate of only 13%. A …

Pancreatic ductal adenocarcinom a (PDA) has two exceptional features. First, it is a highly
lethal disease, with a median survival of less than 6months and a 5-year survival rate less …

Pancreatic ductal adenocarcinoma (PDA) is among the deadliest cancers in the United
States and in the world. Late diagnosis, early metastasis and lack of effective therapy are …