Inhibition of cyclooxygenase-2 activity by celecoxib does not lead to radiosensitization of human prostate cancer cells in vitro
PA Ohneseit, G Krebiehl, K Dittmann… - Radiotherapy and …, 2007 - Elsevier
PURPOSE: To evaluate the potential radiosensitizing effect of the specific COX-2 inhibitor
celecoxib (Celebrex®) on prostate carcinoma cells in vitro. MATERIALS AND METHODS …
celecoxib (Celebrex®) on prostate carcinoma cells in vitro. MATERIALS AND METHODS …
Celecoxib induced tumor cell radiosensitization by inhibiting radiation induced nuclear EGFR transport and DNA-repair: a COX-2 independent mechanism
KH Dittmann, C Mayer, PA Ohneseit, U Raju… - International Journal of …, 2008 - Elsevier
PURPOSE: The purpose of the study was to elucidate the molecular mechanisms mediating
radiosensitization of human tumor cells by the selective cyclooxygenase (COX)-2 inhibitor …
radiosensitization of human tumor cells by the selective cyclooxygenase (COX)-2 inhibitor …
Celecoxib radiosensitizes the human cervical cancer HeLa cell line via a mechanism dependent on reduced cyclo-oxygenase-2 and vascular endothelial growth …
AH Wang, XY Tian, JJ Yu, JQ Mi… - Journal of …, 2012 - journals.sagepub.com
OBJECTIVE: The effects of celecoxib, a selective cyclo-oxygenase-2 (COX-2) inhibitor, on
HeLa cervical cancer cell growth and radiosensitivity were investigated. METHODS …
HeLa cervical cancer cell growth and radiosensitivity were investigated. METHODS …
Nimesulide, a selective COX-2 inhibitor, acts synergistically with ionizing radiation against A549 human lung cancer cells through the activation of caspase-8 and …
BM Kim, J Won, KA Maeng… - International …, 2009 - spandidos-publications.com
Several lines of evidence suggest that non-steroidal anti-inflammatory drugs (NSAIDs) have
a radiosensitizing effect on cancer cells in vitro and in vivo, but little is known about the …
a radiosensitizing effect on cancer cells in vitro and in vivo, but little is known about the …
Celecoxib enhances the radiosensitizing effect of 7-hydroxystaurosporine (UCN-01) in human lung cancer cell lines
YM Kim, IH Jeong, H Pyo - … Journal of Radiation Oncology* Biology* Physics, 2012 - Elsevier
PURPOSE: 7-Hydroxystaurosporine (UCN-01), a Chk1-specific inhibitor, showed promising
in vitro and in vivo chemo-or radiosensitizing activity. However, there have been concerns …
in vitro and in vivo chemo-or radiosensitizing activity. However, there have been concerns …
Celecoxib upregulates ULBP‑1 expression in lung cancer cells via the JNK/PI3K signaling pathway and increases susceptibility to natural killer cell cytotoxicity
J Kim, MH Noh, DY Hur, B Kim, YS Kim… - Oncology …, 2020 - spandidos-publications.com
Lung cancer has the highest cancer mortality rate in the world, and effective therapies are
still required. Cyclooxygenase‑2 (COX‑2) is highly expressed in numerous types of cancer …
still required. Cyclooxygenase‑2 (COX‑2) is highly expressed in numerous types of cancer …
Combined action of celecoxib and ionizing radiation in prostate cancer cells is independent of pro-apoptotic Bax
R Handrick, U Ganswindt, H Faltin, B Goecke… - Radiotherapy and …, 2009 - Elsevier
BACKGROUND AND PURPOSE: The cyclooxygenase-2-inhibitor celecoxib has been
shown to inhibit cell growth and to reduce prostatic intraepithelial neoplasia in mice. The …
shown to inhibit cell growth and to reduce prostatic intraepithelial neoplasia in mice. The …
[HTML][HTML] The molecular mechanisms of celecoxib in tumor development
B Wen, YT Wei, LL Mu, GR Wen, K Zhao - Medicine, 2020 - journals.lww.com
Background: Clinical studies have shown that celecoxib can significantly inhibit the
development of tumors, and basic experiments and in vitro experiments also provide a …
development of tumors, and basic experiments and in vitro experiments also provide a …
Celecoxib a selective COX-2 inhibitor mitigates fibrosis but not pneumonitis following lung irradiation: a histopathological study
R Azmoonfar, P Amini, H Saffar… - Current Drug …, 2020 - ingentaconnect.com
Background: Lung is one of the radiosensitive and late responding organs, and is an
important target for ionizing radiation. Radiation-induced pneumonitis and fibrosis are major …
important target for ionizing radiation. Radiation-induced pneumonitis and fibrosis are major …
Cyclooxygenase-2 inhibitor NS398 enhances radiosensitivity of radioresistant esophageal cancer cells by inhibiting AKT activation and inducing apoptosis
SM Che, XZ Zhang, L Hou, TB Song - Cancer investigation, 2010 - Taylor & Francis
This study aimed to evaluate the radiosensitizing effect of a COX-2 inhibitor, NS398, and its
mechanism in radioresistant esophageal cancer Eca109R50Gy cells. NS398 enhanced …
mechanism in radioresistant esophageal cancer Eca109R50Gy cells. NS398 enhanced …