In-vivo effects and mechanisms of celecoxib-reduced growth of cyclooxygenase-2 (COX-2)-expressing versus COX-2-deleted human HCC xenografts in nude mice
W Cui, SX Hu, ZY Tang, KQ Hu - Anti-cancer drugs, 2008 - journals.lww.com
We previously reported that celecoxib, a cyclooxygenase-2 (COX-2) inhibitor, suppresses
growth of human hepatocellular carcinoma (HCC) cells through both COX-2 dependence …
growth of human hepatocellular carcinoma (HCC) cells through both COX-2 dependence …
Effects of the anti-inflammatory drug celecoxib on cell death signaling in human colon cancer
R Maruyama, Y Kiyohara, Y Kudo… - … Archives of Pharmacology, 2023 - Springer
The anti-inflammatory drug celecoxib, the only inhibitor of cyclooxygenase-2 (COX-2) with
anticancer activity, is used to treat rheumatoid arthritis and can cause endoplasmic reticulum …
anticancer activity, is used to treat rheumatoid arthritis and can cause endoplasmic reticulum …
Down-regulation of glucose-regulated protein (GRP) 78 potentiates cytotoxic effect of celecoxib in human urothelial carcinoma cells
Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor that has been reported to elicit
anti-proliferative response in various tumors. In this study, we aim to investigate the …
anti-proliferative response in various tumors. In this study, we aim to investigate the …
GADD153 mediates celecoxib-induced apoptosis in cervical cancer cells
Celecoxib, a selective cyclooxygenase-2 inhibitor, is known to possess anti-inflammatory
activity and also induces apoptosis in various types of cancer cells. Here, we examined the …
activity and also induces apoptosis in various types of cancer cells. Here, we examined the …
Celecoxib inactivates epithelial–mesenchymal transition stimulated by hypoxia and/or epidermal growth factor in colon cancer cells
C Bocca, F Bozzo, S Cannito, M Parola… - Molecular …, 2012 - Wiley Online Library
Abstract Celecoxib, a selective cyclooxygenase‐2 (COX‐2) inhibitor, has been reported to
exert chemopreventive and antitumor effects on colon cancer, one of the most common solid …
exert chemopreventive and antitumor effects on colon cancer, one of the most common solid …
COX-2-dependent and COX-2-independent mode of action of celecoxib in human liver cancer cells
Abstract Celecoxib (Celebrex (R), Pfizer) is a selective cyclooxygenase-2 (COX-2) inhibitor
with chemopreventive and antitumor effects. However, it is now well known that celecoxib …
with chemopreventive and antitumor effects. However, it is now well known that celecoxib …
[HTML][HTML] Curcumol potentiates celecoxib-induced growth inhibition and apoptosis in human non-small cell lung cancer
F Cai, M Chen, D Zha, P Zhang, X Zhang, N Cao… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Combinatorial therapies that target multiple signaling pathways may provide improved
therapeutic responses over monotherapies. Celecoxib and curcumol are two highly …
therapeutic responses over monotherapies. Celecoxib and curcumol are two highly …
Celecoxib antagonizes the cytotoxicity of cisplatin in human esophageal squamous cell carcinoma cells by reducing intracellular cisplatin accumulation
L Yu, M Chen, Z Li, J Wen, J Fu, D Guo, Y Jiang… - Molecular …, 2011 - ASPET
High cyclooxygenase 2 (COX-2) expression has been reported to be clinically associated
with reduced cisplatin-based therapy efficacy in esophageal cancer. However, the benefit of …
with reduced cisplatin-based therapy efficacy in esophageal cancer. However, the benefit of …
Suppressing growth and invasion of human hepatocellular carcinoma cells by celecoxib through inhibition of cyclooxygenase-2
Purpose: Biomarkers are lacking in hepatocellular carcinoma (HCC). Cyclooxygenase-2
(COX-2) and its metabolites play crucial roles in the process of inflammation-tumor …
(COX-2) and its metabolites play crucial roles in the process of inflammation-tumor …
The role of celecoxib in Rad51 expression and cell survival affected by gefitinib in human non-small cell lung cancer cells
JC Ko, LH Wang, JY Jhan, SC Ciou, JH Hong, ST Lin… - Lung cancer, 2009 - Elsevier
Celecoxib (CelebrexR) is a cyclooxygenase-2 (COX-2) selective inhibitor and gefitinib
(IressaR, ZD1839) is a selective epidermal growth factor receptor (EGFR) tyrosine kinase …
(IressaR, ZD1839) is a selective epidermal growth factor receptor (EGFR) tyrosine kinase …