The 5xFAD mouse model of Alzheimer's disease (AD) rapidly develops AD‐related neuro‐
behavioral pathology. Learning and memory impairments in 5xFAD mice, however, are not …

In the present report, we extend previous findings in the 5XFAD mouse model with regard to
a characterization of behavioral deficits and neuropathological alterations. We demonstrate …

Alzheimer's disease (AD) is a neurodegenerative disorder that leads to age‐related
cognitive and sensori‐motor dysfunction. There is an increased understanding that motor …

Motor problems occur early in some patients with Alzheimer's disease (AD) and as the
disease progresses many patients develop motor dysfunction. Motor dysfunction has been …

Transgenic animal models of Alzheimer's disease (AD) are widely used to investigate
mechanisms of pathophysiology and cognitive dysfunctions. A model with a very early …

Alzheimer's disease is a progressive neurodegenerative disease that manifests as memory
loss, cognitive dysfunction, and dementia. Animal models of Alzheimer's disease have been …

Transgenic mouse models of Alzheimer's disease (AD), such as the 3xTg-AD mice, are
instrumental for elucidating genetic, pharmacologic, environmental, and behavioral factors …

Although animal models of Alzheimer's disease (AD) recapitulate β-amyloid-dependent
hippocampal synaptic and cognitive dysfunctions, it is poorly understood how cortex …

Abstract 5XFAD is an early-onset mouse transgenic model of Alzheimer disease (AD). Up to
now there are no studies that focus on the epigenetic changes produced as a result of Aβ-42 …

A promising direction in the research on Alzheimer's Disease (AD) is the identification of
biomarkers that better inform the disease progression of AD. However, the performance of …