Alternative splicing of RNAs generates isoform diversity, resulting in different proteins that
are necessary for maintaining cellular function and identity. The discovery of alternative …

Alternative splicing is an important source of heterogeneity underlying gene expression
between individual cells but remains an understudied area due to the paucity of …

RNA splicing is a fundamental regulatory process of gene expression and plays a pivotal
role in transcriptome complexity, cell-fate determination, and organism development. The …

Alternative splicing contributes to the majority of protein diversity in higher eukaryotes by
allowing one gene to generate multiple distinct protein isoforms. It adds another regulation …

Alternative splicing is widely recognized for its roles in regulating genes and creating gene
diversity. Consequently the identification and quantification of differentially spliced …

Since the discovery of alternative splicing in the late 1970s, a great number of alternatively
spliced transcripts have emerged; this number has exponentially increased with the …

Alternative splicing (AS) generates isoform diversity for cellular identity and homeostasis in
multicellular life. Although AS variation has been observed among single cells, little is …

This chapter provides a review of recent advances in understanding the importance of
alternative pre-messenger RNA splicing in stem cell biology. The majority of transcribed pre …

Although alternative splicing is a fundamental and pervasive aspect of gene expression in
higher eukaryotes, it is often omitted from single-cell studies due to quantification challenges …

Alternative splicing of pre-messenger RNA (pre-mRNA) is a fundamental mechanism of
gene regulation in higher eukaryotes. In addition to creating protein diversity, alternative …