Alternative splicing represents an important level of the regulation of gene function in
eukaryotic organisms. It plays a critical role in virtually every biological process within an …

Alternative splicing is a major cellular mechanism in metazoans for generating proteomic
diversity. A large proportion of protein-coding genes in multicellular organisms undergo …

[Frontiers in Bioscience 12, 4034-4041, May 1, 2007] 4034 Genomic analysis of RNA
alternative splicing in cancers Yi Xing Depar Page 1 [Frontiers in Bioscience 12, 4034-4041 …

Pre-messenger RNA splicing is a fine-tuned process that generates multiple functional
variants from individual genes. Various cell types and developmental stages regulate …

Alternative splicing is crucial in gene regulation, with significant implications in clinical
settings and biotechnology. This review article compiles bioinformatics RNA-seq tools for …

Understanding the molecular mechanisms responsible for the regulation of the
transcriptome present in eukaryotic cells is one of the most challenging tasks in the …

Cis-acting short sequence motifs play important roles in alternative splicing. It is now
possible to identify such sequence motifs as conserved sequence patterns in genome …

Stem cells have the surprising potential to develop into many different cell types. Therefore,
major research efforts have focused on transplantation of stem cells and/or derived …

Alternative splicing is an important gene regulatory mechanism that dramatically increases
the complexity of the proteome. However, how alternative splicing is regulated and how …

Motivation. Alternative splicing events (ASEs) are prevalent in the transcriptome of
eukaryotic species and are known to influence many biological phenomena. The …