Biomarkers of environmental toxicants: exposure and biological effects
RJ Turesky, K Lu - Toxics, 2020 - mdpi.com
Biomarkers of environmental toxicants are measures of exposures and effects, some of
which can serve to assess disease risk and interindividual susceptibilities. Metabolites …
which can serve to assess disease risk and interindividual susceptibilities. Metabolites …
Linking Toxicology and Human Health Through the Exposome
EJ Moran - Chemical Research in Toxicology, 2024 - ACS Publications
Current analytical technology and continuing maturation of-omics methodology have
enabled detailed assessment of human exposure via the exposome. Topics exploring the …
enabled detailed assessment of human exposure via the exposome. Topics exploring the …
The exposome and health: Where chemistry meets biology
Despite extensive evidence showing that exposure to specific chemicals can lead to
disease, current research approaches and regulatory policies fail to address the chemical …
disease, current research approaches and regulatory policies fail to address the chemical …
Application of metabolomics to characterize environmental pollutant toxicity and disease risks
The increased incidence of non-communicable human diseases may be attributed, at least
partially, to exposures to toxic chemicals such as persistent organic pollutants (POPs), air …
partially, to exposures to toxic chemicals such as persistent organic pollutants (POPs), air …
Biomarkers in toxicology and risk assessment
BA Fowler - … , Clinical and Environmental Toxicology: Volume 3 …, 2012 - Springer
Over the last 30 years, the field of biomarkers has greatly expanded as early and specific
endpoints for monitoring cellular responses to various disease states and exposures to …
endpoints for monitoring cellular responses to various disease states and exposures to …
Metabolic signatures of the exposome—quantifying the impact of exposure to environmental chemicals on human health
Human health and well-being are intricately linked to environmental quality. Environmental
exposures can have lifelong consequences. In particular, exposures during the vulnerable …
exposures can have lifelong consequences. In particular, exposures during the vulnerable …
Using exposomics to assess cumulative risks and promote health
MT Smith, R de la Rosa… - Environmental and …, 2015 - Wiley Online Library
Under the exposome paradigm all nongenetic factors contributing to disease are considered
to be 'environmental'including chemicals, drugs, infectious agents, and psychosocial stress …
to be 'environmental'including chemicals, drugs, infectious agents, and psychosocial stress …
[HTML][HTML] Blurred lines: Crossing the boundaries between the chemical exposome and the metabolome
C Balcells, Y Xu, R Gil-Solsona, L Maitre… - Current opinion in …, 2024 - Elsevier
The aetiology of every human disease lies in a combination of genetic and environmental
factors, each contributing in varying proportions. While genomics investigates the former, a …
factors, each contributing in varying proportions. While genomics investigates the former, a …
Blurred lines: Crossing the boundaries between the chemical exposome and the metabolome
C Balcells Nadal, Y Xu, R Gil Solsona… - Curr Opin Chem Biol …, 2024 - repositori.upf.edu
The aetiology of every human disease lies in a combination of genetic and environmental
factors, each contributing in varying proportions. While genomics investigates the former, a …
factors, each contributing in varying proportions. While genomics investigates the former, a …
[HTML][HTML] Chemical safety and the exposome
O Karlsson - Emerging Contaminants, 2023 - Elsevier
Air pollution and rapid chemical intensification are major threats to the environment and
human health. Today, we have produced over 350,000 chemicals, and current testing …
human health. Today, we have produced over 350,000 chemicals, and current testing …