Minocycline and doxycycline: more than antibiotics

S Singh, D Khanna, S Kalra - Current Molecular Pharmacology, 2021 - ingentaconnect.com
Minocycline and doxycycline both are second-generation tetracycline antibiotics with similar
chemical structures and comparable antibacterial spectrum. Minocycline has also emerged …

Minocycline: far beyond an antibiotic

N Garrido‐Mesa, A Zarzuelo… - British journal of …, 2013 - Wiley Online Library
Minocycline is a second‐generation, semi‐synthetic tetracycline that has been in therapeutic
use for over 30 years because of its antibiotic properties against both gram‐positive and …

Minocycline in neurodegenerative and psychiatric diseases: an update

D Romero‐Miguel, N Lamanna‐Rama… - European Journal of …, 2021 - Wiley Online Library
Background and purpose Minocycline is a broad‐spectrum antibiotic, effective as a chronic
treatment for recurrent bacterial infections. Beyond its antibiotic action, minocycline also has …

The potential of minocycline for neuroprotection in human neurologic disease

D Zemke, A Majid - Clinical neuropharmacology, 2004 - journals.lww.com
Minocycline is a member of the tetracycline class of molecules with broad-spectrum
antibiotic activity. The unique properties of minocycline result in increased tissue distribution …

Reconnoitering the transformative journey of minocycline from an antibiotic to an antiepileptic drug

T Singh, S Thapliyal, S Bhatia, V Singh, M Singh… - Life Sciences, 2022 - Elsevier
Minocycline, a second-generation tetracycline antibiotic is being widely tested in animals as
well as clinical settings for the management of multiple neurological disorders. The drug has …

[HTML][HTML] Minocycline as treatment for psychiatric and neurological conditions: a systematic review and meta-analysis

B Panizzutti, D Skvarc, S Lin, S Croce… - International Journal of …, 2023 - mdpi.com
Minocycline has anti-inflammatory, antioxidant, and anti-apoptotic properties that explain the
renewed interest in its use as an adjunctive treatment for psychiatric and neurological …

[HTML][HTML] The therapeutic role of minocycline in Parkinson's disease

S Cankaya, B Cankaya, U Kilic, E Kilic, B Yulug - Drugs in context, 2019 - ncbi.nlm.nih.gov
Minocycline, a semisynthetic tetracycline-derived antibiotic, has been shown to exert anti-
apoptotic, anti-inflammatory, and antioxidant effects. Furthermore, there is rapidly growing …

What is behind the non-antibiotic properties of minocycline?

N Garrido-Mesa, A Zarzuelo, J Galvez - Pharmacological research, 2013 - Elsevier
Minocycline is a second-generation, semi-synthetic tetracycline that has been in use in
therapy for over 30 years for its antibiotic properties against both Gram-positive and Gram …

Prospects for minocycline neuroprotection

JM Plane, Y Shen, DE Pleasure, W Deng - Archives of neurology, 2010 - jamanetwork.com
The lack of robust treatment options available for neurodegenerative diseases, stroke, and
central nervous system (CNS) trauma, all of which often involve both inflammation and …

Impact of minocycline on neurodegenerative diseases in rodents: a meta-analysis

C Li, K Yuan, H Schluesener - Reviews in the Neurosciences, 2013 - degruyter.com
Minocycline is a semisynthetic second-generation tetracycline derivative, and many
publications provide evidence of its successful neuroprotection in a variety of animal …