Post-translational protein modifications by ubiquitin, SUMO and other ubiquitin-like modifiers
is common and essential for all eukaryotic organisms. Ubiquitin, SUMO and other ubiquitin …

Post-translational modification by small ubiquitin-related modifier (SUMO) is a key regulator
of cell physiology, modulating protein-protein and protein-DNA interactions. Recently …

▪ Abstract SUMO (small ubiquitin-related modifier) is the best-characterized member of a
growing family of ubiquitin-related proteins. It resembles ubiquitin in its structure, its ability to …

SUMO (small ubiquitin-related modifier) is a highly conserved eukaryotic member of the
family of ubiquitin-related proteins. Despite limited sequence similarity, SUMO and ubiquitin …

ABSTRACT SUMO, a small ubiquitin-like modifier, is a highly conserved post translational
modification and a central regulatory system in eukaryotes. Sumoylation modulates the …

Although the post-translational modification of proteins with small ubiquitin-like modifier
(SUMO) has a role in many biological processes, it was thought that SUMO, unlike ubiquitin …

Posttranslational modification by ubiquitin and SUMO is recognized as an effective means of
controlling the stability, localization or activity of intracellular proteins, thereby contributing to …

Covalent modification of cellular proteins by the ubiquitin-like modifier SUMO regulates
various cellular processes, such as nuclear transport, signal transduction, stress response …

The proteasome is an ATP-dependent multisubunit selfcompartmentalised protease
complex. It is the major regulator of intracellular proteins turnover. The majority of proteins …

Small ubiquitin-related modifiers (SUMOs) are important regulator proteins. Caenorhabditis
elegans contains a single SUMO ortholog, SMO-1, necessary for the reproduction of C …