Discrepancy between equations estimating kidney function in geriatric care: a study of implications for drug prescription

F Guerville, C Roubaud-Baudron, S Duc, N Salles… - Drugs & Aging, 2019 - Springer
Background In older patients, the agreement is low between creatinine clearance estimated
with the Cockcroft-Gault equation (eCrCl) and glomerular filtration rate estimated with the …

Kidney function and clinical recommendations of drug dose adjustment in geriatric patients

M Karsch-Völk, E Schmid, S Wagenpfeil, K Linde… - BMC geriatrics, 2013 - Springer
Background In elderly patients chronic kidney disease often limits drug prescription. As
several equations for quick assessment of kidney function by estimating glomerular filtration …

Estimated glomerular filtration rate leads to higher drug dose recommendations in the elderly compared with creatinine clearance

JQ Hudson, JR Bean, CF Burger… - … Journal of Clinical …, 2015 - Wiley Online Library
Purpose The elderly are at risk for adverse drug events because of inappropriate dosing of
renally eliminated medications. The purpose of this study was to evaluate differences in …

Implications of using the MDRD or CKD‐EPI equation instead of the Cockcroft–Gault equation for estimating renal function and drug dosage adjustment in elderly …

E Cartet‐Farnier, L Goutelle‐Audibert… - Fundamental & …, 2017 - Wiley Online Library
The objectives of this study were to compare the estimations of renal function obtained with
six equations, including the Cockcroft–Gault (CG), Modification of Diet in Renal Disease …

Discrepancies among equations to estimate the glomerular filtration rate for drug dosing decision making in aged patients: a cross sectional study

MM Castel-Branco, M Lavrador, AC Cabral… - International Journal of …, 2024 - Springer
Background Patients often require adjustments to drug doses due to impaired renal function.
Glomerular filtration rate (GFR) estimation using various equations can result in …

Glomerular filtration rate equations overestimate creatinine clearance in older individuals enrolled in the Baltimore Longitudinal Study on Aging: impact on renal drug …

TC Dowling, ES Wang, L Ferrucci… - … : The Journal of Human …, 2013 - Wiley Online Library
Objectives To evaluate the performance of kidney function estimation equations and to
determine the frequency of drug dose discordance in an older population. Design Cross …

Clinical factors increasing discrepancies of renal function assessment with MDRD and Cockcroft–Gault equations in old individuals

J Chudek, A Kolonko, AJ Owczarek… - European Geriatric …, 2018 - Springer
Purpose Abstract In a daily clinical practice, glomerular filtration rate (GFR) is still estimated
on the basis of short MDRD formula, whereas medications' Summaries of Product …

Comparison of estimated glomerular filtration rate with estimated creatinine clearance in the dosing of drugs requiring adjustments in elderly patients with declining …

WJ Spruill, WE Wade, HH Cobb III - The American journal of geriatric …, 2008 - Elsevier
Background: The National Kidney Foundation's practice guidelines for chronic kidney
disease recommend using the Modification of Diet in Renal Disease (MDRD) equation for …

Kidney function estimates using cystatin C versus creatinine: Impact on medication prescribing in acutely hospitalized elderly patients

E Iversen, AC Bodilsen, HH Klausen… - Basic & clinical …, 2019 - Wiley Online Library
Background Medication errors due to inaccurate measures of kidney function are common
among elderly patients. We investigated differences between estimated glomerular filtration …

Drugs dosing in geriatric patients depending on kidney function estimated by MDRD and cockroft-gault formulas

M Szymala-Pędzik, J Żórawska… - Clinical Interventions in …, 2021 - Taylor & Francis
Introduction According to the current data, regardless of the method used to estimate GFR,
the differences between the obtained results should be insignificant and do not imply …