This study aimed to investigate whether matrine (Ma) attenuates isoproterenol (ISO)-induced
acute myocardial hypertrophy via activating Akt/mTOR/p70S6K/eIF4E signaling pathway in …

Growth factors and inflammatory Ras homolog gene family member A (RhoA)/coiled-coil
containing protein kinase 1 (ROCK1) pathway have been shown to regulate isoproterenol …

Objectives This study was designed to investigate the cardioprotective effects of matrine on
regulation of endothelial nitric oxide synthase (eNOS) and asymmetric dimethylarginine …

Background Matrine might play a vital role in cardiovascular diseases progression and
treatment. Objectives We aimed to explore the protective effects and potential mechanism of …

Habitual chewing of the areca nut increases the risk of mortality owing to cardiovascular
disease, but few reports have revealed the cardiotoxicity mechanism of the areca nut …

Background: Myocardial hypertrophy, when pathological and sustained, is one of the
predictors of cardiovascular morbidity. Telmisartan (TEL) and trimetazidine (TMZ) are drugs …

Objectives This study was designed to explore the effect and mechanism of matrine, an
active component of Chinese traditional medicine, on isoproterenol-induced acute …

Maslinic acid (MA), a pentacyclic triterpenoid, has been reported to exert broad
pharmacological properties. However, it is still unclear whether MA exhibits protective effects …

Pathological cardiac fibrosis is a common feature in multiple cardiovascular diseases that
contributes to the occurrence of heart failure and life-threatening arrhythmias. Our previous …

Background Etomidate has been shown to reduce ischemia/reperfusion (I/R) injury in
several tissues. Here we aimed to investigate the protective effects of etomidate on I/R injury …