Characterization and biocompatibility of nanohybrid scaffold prepared via in situ crystallization of hydroxyapatite in chitosan matrix

J Chen, K Nan, S Yin, Y Wang, T Wu… - Colloids and Surfaces B …, 2010 - Elsevier
Hydroxyapatite (HAP) precursor solution was first mixed with an acetic acid chitosan (CS)
solution. The mixture was then lyophilized to form the original scaffold, which stored the HAP …

Formation of nano-hydroxyapatite crystal in situ in chitosan–pectin polyelectrolyte complex network

J Li, D Zhu, J Yin, Y Liu, F Yao, K Yao - Materials Science and Engineering …, 2010 - Elsevier
Hydroxyapatite (HA)/polysaccharide composites have been widely used in bone tissue
engineering due to their chemical similarity to natural bone. Polymer matrix-mediated …

[HTML][HTML] Preparation and biological properties of a novel composite scaffold of nano-hydroxyapatite/chitosan/carboxymethyl cellulose for bone tissue engineering

J Liuyun, L Yubao, X Chengdong - Journal of biomedical science, 2009 - Springer
In this study, we report the physico-chemical and biological properties of a novel
biodegradable composite scaffold made of nano-hydroxyapatite and natural derived …

In situ fabrication of nano-hydroxyapatite in a macroporous chitosan scaffold for tissue engineering

JD Chen, Y Wang, X Chen - Journal of Biomaterials Science …, 2009 - Taylor & Francis
A chitosan (CS)/hydroxyapatite (HAP) nanohybrid scaffold with high porosity and
homogeneous nanostructure was fabricated through a bionic treatment combined with …

[HTML][HTML] Preparation and characterization of homogeneous hydroxyapatite/chitosan composite scaffolds via in-situ hydration

H Li, CR Zhou, MY Zhu, JH Tian, JH Rong - Journal of Biomaterials and …, 2010 - scirp.org
Hydroxyapatite (HAP)/Chitosan (CS) composite is a biocompatible and bioactive material for
tissue engineering. A novel homogeneous HAP/CS composite scaffold was developed via …

Novel chitosan/agarose/hydroxyapatite nanocomposite scaffold for bone tissue engineering applications: Comprehensive evaluation of biocompatibility and …

P Kazimierczak, A Benko, M Nocun… - International journal of …, 2019 - Taylor & Francis
Background Nanocomposites produced by reinforcement of polysaccharide matrix with
nanoparticles are widely used in engineering of biomaterials. However, clinical applications …

Nano-hydroxyapatite formation via co-precipitation with chitosan-g-poly(N-isopropylacrylamide) in coil and globule states for tissue engineering application

Y Yu, H Zhang, H Sun, D Xing, F Yao - Frontiers of Chemical Science and …, 2013 - Springer
With the excellent biocompatibility and osteoconductivity, nano-hydroxyapatite (nHA) has
shown significant prospect in the biomedical applications. Controlling the size, crystallinity …

Bioinspired double polysaccharides-based nanohybrid scaffold for bone tissue engineering

T Fan, J Chen, P Pan, Y Zhang, Y Hu, X Liu… - Colloids and Surfaces B …, 2016 - Elsevier
The fabrication of bone scaffolds with interconnected porous structure, adequate mechanical
properties and excellent biocompatibility presents a great challenge. Herein, a hybrid …

Biomimetic mineralization on natural and synthetic polymers to prepare hybrid scaffolds for bone tissue engineering

L Zou, Y Zhang, X Liu, J Chen, Q Zhang - Colloids and Surfaces B …, 2019 - Elsevier
To mimic the mineral component and the microstructure of natural bone, nanohydroxyapatite
(nHAP)/polymer (natural and synthetic materials) composite scaffolds with micropore …

Fabrication of biocomposite scaffolds made with modified hydroxyapatite inclusion of chitosan-grafted-poly (methyl methacrylate) for bone tissue engineering

T Tithito, P Suntornsaratoon… - Biomedical …, 2019 - iopscience.iop.org
In the present study, composite scaffolds of chitosan-graft-poly (methyl methacrylate)(Chi-g-
PMMA) and mineral ions-loaded hydroxyapatite (mHA)(obtained by the hydrothermal …