Purpose: Tumor infiltrating T lymphocytes in colorectal cancer (CRC) have prognostic
impact, but the role of natural killer (NK) cells in CRC tissue is unclear. The contribution of …

Recent evidence suggests that natural killer (NK) cells are typically defective in infiltrating
solid tumors, with the exception of gastrointestinal stromal tumors (GIST). Interestingly …

Background The association between natural killer (NK) cells and survival in colorectal
cancer (CRC) patients remains controversial. This study aimed to clarify the prognostic value …

The clinical outcome of colorectal cancer (CRC) is associated with the immune response;
thus, these tumors could be responsive to different immune therapy approaches. Natural …

A majority of colorectal adenocarcinomas displays diminished MHC class I expression,
making them particularly vulnerable for NK cell-mediated killing. Generally, these tumors …

BACKGROUND Natural killer (NK) cells have a spontaneous cytotoxic capacity against
tumor cells. These cells represent a small proportion of human colon carcinoma‐infiltrating …

Objective As the development and progression of colorectal cancer (CRC) are known to be
affected by the immune system, cell subsets such as T cells, natural killer (NK) cells, and …

Despite NK cells being originally identified because of their ability to kill tumor cells in vitro,
only limited information is available on NK cells infiltration of malignant tumors, especially in …

Gastrointestinal cancer is one of the leading health problems worldwide, with a high
morbidity and mortality. To date, harnessing both the innate and adaptive immune system …

Although tumor-infiltrating T cells hold a beneficial prognostic role in colorectal cancer, other
lymphocytic populations are less characterized. We developed a multiplexed …