Delay aging, especially in healthy life extension, brought the most interest to the medical
field. Searching for anti-aging drugs with relative safety profiles bring natural products in …

There is growing interest in pharmacological interventions directly targeting the aging
process. Pharmacological interventions against aging should be efficacious when started in …

Drugs or compounds have been shown to promote longevity in various approaches. We
used Drosophila to explore novel natural compounds can be applied to anti-aging. Here we …

Species from lower invertebrates to a spectrum of mammals show antiaging health benefits
of phytochemical (s). Here, we explored the pro-longevity effects of a natural triterpenoid …

A major goal of healthy aging is to prevent declining resilience and increasing frailty, which
are associated with many chronic diseases and deterioration of stress response. Here, we …

Highlights•Calycosin could function as an antioxidant to extend the lifespan of
Caenorhabditis elegans.•Calycosin requires insulin signaling to promote lifespan …

Astaxanthin (AX) is a xanthophyll carotenoid that can effectively inhibit the production of
peroxides and thereby protect the body from oxidative damage. In recent years, AX had …

Aging is the major risk factor for many human diseases and degeneration. Thus, clinically
effective medicine could delay the process of aging and aging-related diseases are …

Low temperatures delay aging and promote longevity in many organisms. However, the
metabolic and homeostatic aspects of low-temperature–induced longevity remain poorly …

Dioscin (DS) is a steroidal saponin present in a number of medicinal plants and has been
shown to exert anticancer, antifungal and antiviral effects. The present study aimed to …