Neuropeptidomic profiling and localization in the crustacean cardiac ganglion using mass spectrometry imaging with multiple platforms

K DeLaney, L Li - Journal of the American Society for Mass …, 2020 - ACS Publications
The crustacean cardiac neuromuscular system is a useful model for studying how neural
circuits generate behavior, as it is comprised of a simple ganglion containing nine neurons …

An Updated Guide to the Identification, Quantitation, and Imaging of the Crustacean Neuropeptidome

W Wu, L Fields, K DeLaney, AR Buchberger… - Peptidomics: Methods and …, 2024 - Springer
Crustaceans serve as a useful, simplified model for studying peptides and neuromodulation,
as they contain numerous neuropeptide homologs to mammals and enable …

A multi-scale strategy for discovery of novel endogenous neuropeptides in the crustacean nervous system

C Jia, CB Lietz, H Ye, L Hui, Q Yu, S Yoo, L Li - Journal of proteomics, 2013 - Elsevier
The conventional mass spectrometry (MS)-based strategy is often inadequate for the
comprehensive characterization of various size neuropeptides without the assistance of …

Mapping of neuropeptides in the crustacean stomatogastric nervous system by imaging mass spectrometry

H Ye, L Hui, K Kellersberger, L Li - Journal of the American …, 2012 - ACS Publications
Considerable effort has been devoted to characterizing the crustacean stomatogastric
nervous system (STNS) with great emphasis on comprehensive analysis and mapping …

High throughput in situ DDA analysis of neuropeptides by coupling novel multiplex mass spectrometric imaging (MSI) with gas-phase fractionation

C OuYang, B Chen, L Li - Journal of The American Society for …, 2015 - ACS Publications
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometric imaging (MSI) is a
powerful tool to map the spatial distribution of biomolecules on tissue sections. Recent …

A Multifaceted Mass Spectrometric Method to Probe Feeding Related Neuropeptide Changes in Callinectes sapidus and Carcinus maenas

Y Zhang, K DeLaney, L Hui, J Wang… - Journal of The …, 2018 - ACS Publications
Food intake is regulated by various neuromodulators, including numerous neuropeptides.
However, it remains elusive at the molecular and cellular level as to how these important …

Mass spectrometric analysis of spatio-temporal dynamics of crustacean neuropeptides

C OuYang, Z Liang, L Li - Biochimica et Biophysica Acta (BBA)-Proteins …, 2015 - Elsevier
Neuropeptides represent one of the largest classes of signaling molecules used by nervous
systems to regulate a wide range of physiological processes. Over the past several years …

Data independent acquisition mass spectrometry method for improved neuropeptidomic coverage in crustacean neural tissue extracts

K DeLaney, L Li - Analytical chemistry, 2019 - ACS Publications
Neuropeptides are an important class of signaling molecules in the nervous and
neuroendocrine system, but they are challenging to study due to their low concentration in …

Imaging mass spectrometry of neuropeptides in decapod crustacean neuronal tissues

SS DeKeyser, KK Kutz-Naber, JJ Schmidt… - Journal of proteome …, 2007 - ACS Publications
Imaging mass spectrometry (IMS) of neuropeptides in crustacean neuronal tissues was
performed on a MALDI-TOF/TOF instrument. Sample preparation protocols were developed …

Mass spectrometric imaging of neuropeptides in decapod crustacean neuronal tissues

R Chen, SS Cape, RM Sturm, L Li - Mass spectrometry imaging: principles …, 2010 - Springer
The emerging technology mass spectrometric imaging (MSI) provides an attractive
opportunity to detect and probe the molecular content of tissues in an anatomical context …