The Role of Abnormal Placentation in Congenital Heart Defects
JA Courtney - 2021 - search.proquest.com
Congenital heart disease (CHD) is the most common birth defect, and unexplained CHD
may be secondary to undiscovered roles of gene/environment interactions. Improper …
may be secondary to undiscovered roles of gene/environment interactions. Improper …
Conditional mutation of Hand1 in the mouse placenta disrupts placental vascular development resulting in fetal loss in both early and late pregnancy
Congenital heart defects (CHD) affect approximately 1% of all live births, and often require
complex surgeries at birth. We have previously demonstrated abnormal placental …
complex surgeries at birth. We have previously demonstrated abnormal placental …
Prenatal congenital heart disease and placental phenotypes: preserved neonatal weight despite small placentas
A Desmond, H Imany-Shakibai, D Wong, L Kwan… - JACC: Advances, 2023 - jacc.org
Background Congenital heart disease (CHD) affects 8 in 1,000 live births with significant
postnatal implications including growth failure, neurodevelopmental delay, and mortality …
postnatal implications including growth failure, neurodevelopmental delay, and mortality …
Placenta crucially affects formation of fetal congenital heart disease
VI Tsibizova, TM Pervunina, VA Artemenko… - Obstetrics, Gynecology …, 2022 - gynecology.su
It has been increasingly recognized that structural abnormalities and functional changes in
the placenta can adversely affect developing fetal heart. In this article, we examine a role of …
the placenta can adversely affect developing fetal heart. In this article, we examine a role of …
Evidence for uteroplacental malperfusion in fetuses with major congenital heart defects
Aims Fetuses affected by congenital heart defects (CHD) are considered to be at increased
risk of fetal growth restriction and intrauterine demise. Whether these risks are a direct …
risk of fetal growth restriction and intrauterine demise. Whether these risks are a direct …
The role of abnormal placentation in congenital heart disease; cause, correlate, or consequence?
JA Courtney, JF Cnota, HN Jones - Frontiers in Physiology, 2018 - frontiersin.org
Congenital heart disease (CHD) is the most common birth defect, affecting~ 1% of all live
births (van der Linde et al.,). Despite improvements in clinical care, it is the leading cause of …
births (van der Linde et al.,). Despite improvements in clinical care, it is the leading cause of …
[HTML][HTML] Placental abnormalities in congenital heart disease
NN Andescavage, C Limperopoulos - Translational pediatrics, 2021 - ncbi.nlm.nih.gov
Congenital heart disease (CHD) remains the most common birth defect in infants, and
critical CHD is associated with significant rates of morbidity and mortality. With the advent of …
critical CHD is associated with significant rates of morbidity and mortality. With the advent of …
Abnormalities of placental development and function are associated with the different fetal growth patterns of hypoplastic left heart syndrome and transposition of the …
J Courtney, W Troja, KJ Owens, HM Brockway… - Placenta, 2020 - Elsevier
Background Birthweight is a critical predictor of congenital heart disease (CHD) surgical
outcomes. Hypoplastic left heart syndrome (HLHS) is cyanotic CHD with known fetal growth …
outcomes. Hypoplastic left heart syndrome (HLHS) is cyanotic CHD with known fetal growth …
Interdependence of placenta and fetal cardiac development
The placenta and fetal heart undergo development concurrently during early pregnancy,
and, while human studies have reported associations between placental abnormalities and …
and, while human studies have reported associations between placental abnormalities and …
Shared developmental pathways of the placenta and fetal heart
A Mahadevan, A Tipler, H Jones - Placenta, 2023 - Elsevier
Congenital heart defects (CHD) remain the most common class of birth defect worldwide,
affecting 1 in every 110 live births. A host of clinical and morphological indicators of …
affecting 1 in every 110 live births. A host of clinical and morphological indicators of …
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